Chinese Journal of Tissue Engineering Research ›› 2019, Vol. 23 ›› Issue (34): 5442-5446.doi: 10.3969/j.issn.2095-4344.1406

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Application of 3D printing technology in reduction and fixation of zygomatic arch fracture

Ou Bangbin, Li Yingxia, Liu Tingting
  

  1. Department of Maxillofacial Surgery, Xingyi People's Hospital, Xingyi 562400, Guizhou Province, China
  • Received:2019-04-15 Online:2019-12-08 Published:2019-12-08
  • Contact: Ou Bangbin, Department of Maxillofacial Surgery, Xingyi People's Hospital, Xingyi 562400, Guizhou Province, China
  • About author:Ou Bangbin, Associate chief physician, Department of Maxillofacial Surgery, Xingyi People's Hospital, Xingyi 562400, Guizhou Province, China

Abstract:

BACKGROUND: In the treatment of zygomatic arch fracture, due to the special anatomical structure of zygomatic arch and the strict requirement of maxillofacial morphology recovery, it is necessary for the operator to accurately locate the fracture location, displacement degree and fracture line to implement precise reduction and achieve ideal surgical results.
OBJECTIVE: To investigate the application value of 3D printing technology in reduction and fixation of zygomatic arch fracture.
METHODS: Seventy-six patients with zygomatic arch fracture admitted to Xingyi People's Hospital from January 2017 to June 2018 were divided into two groups by random number table method. In the control group (n=38), patients received traditional open reduction and internal fixation with titanium plate. In the observation group (n=38), open reduction and internal fixation with titanium plate was designed and implemented on a pre-made 3D fracture model. The fracture reduction effect was evaluated in these two groups. Complications were recorded. Prior to and 8 days after surgery, fasting venous blood was collected to detect serum levels of bone morphogenetic protein 2 and vascular endothelial growth factor. The time of bone healing was judged by imaging examination. This study was approved by the Ethics Committee of Xingyi People's Hospital, China.
RESULTS AND CONCLUSION: The excellent and good rate of fracture reduction in the observation group was higher than that in the control group (92%, 76%, P < 0.05); the healing time in the observation group was shorter than that in the control group [(32.83±4.26), (45.28±6.71) days, P < 0.05]. At 8 days after surgery, serum levels of bone morphogenetic protein 2 and vascular endothelial growth factor were significantly higher than those before surgery in each group (P < 0.05). At 8 days after surgery, serum levels of bone morphogenetic protein 2 and vascular endothelial growth factor in the observation group were significantly higher than those in the control group (P < 0.05). The incidence of complications in the observation group was significantly lower than that in the control group (8%, 26%, P < 0.05). The results suggest that in the treatment of zygomatic arch fracture, application of 3D printing technology can effectively enhance fracture reduction and healing, and reduce the incidence of surgery-related complications.

Key words: zygomatic arch, fracture, fixation, reduction, 3D printing, titanium plate, fracture healing, complications, bone morphogenetic protein 2 and vascular endothelial growth factor

CLC Number: 

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R459.9