Injectable bone graft for the repair of nonunion of midshaft clavicular fracture after internal fixation

doi:10.3969/j.issn.2095-4344.2356

Abstract

Abstract:

BACKGROUND: Treatment of nonunion of clavicular fractures usually requires the insertion of bone material to facilitate bone healing. Injectable bone grafts have been successfully used in the treatment of limb fractures and lumbar fusion. However, there are few studies on its use in the treatment of nonunion.

OBJECTIVE: To investigate the clinical effect of injection bone graft in the treatment of nonunion of clavicle fracture after internal fixation.

METHODS: Totally 13 patients (9 males and 4 females aged 19-54 years old) with nonunion after internal fixation of clavicular fractures in the middle segment of the clavicle, who were treated in the No. 908 Hospital of Joint Logistic Support Force of Chinese PLA from January 2015 to December 2016, were selected. All of them were treated with ALLOMATRIX^® injection bone graft. Postoperative follow-up was conducted for 12 months. The fracture healing quality was evaluated by Lane-Sandhu X-ray score, and the shoulder joint function was evaluated by Constant score. This experiment was approved by the Ethics Committee of No. 908 Hospital of Joint Logistic Support Force of Chinese PLA.

RESULTS AND CONCLUSION: (1) All the 13 patients received osseous healing, which lasted 8-16 weeks, and no complications such as infection, dislocation, or fixator loosening occurred. (2) The total Lane-Sandhu X-ray score of 13 patients at 3 months and the last follow-up was higher than that before the operation (P < 0.05). (3) The total Constant score of shoulder joint function in 13 patients was higher than that before surgery at 3 months after surgery and at the last follow-up (P < 0.05). (4) The results showed that ALLOMATRIX^® injection bone graft could be used to treat clavicular nonunion.

Key words: bone">, , material">, , nonunion">, , implant">, , fixation">, , internal fixation">, , clavicle">, , fracture

CLC Number:

Chen Shaobo, Shuang Feng, Hu Wei, Li Hao, Shao Yinchu. Injectable bone graft for the repair of nonunion of midshaft clavicular fracture after internal fixation[J]. Chinese Journal of Tissue Engineering Research, 2020, 24(34): 5473-5477.

Figures/Tables 4

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