Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (16): 2620-2624.doi: 10.3969/j.issn.2095-4344.2261

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Meta-analysis of dental implantation success rate in diabetic patients with 6% < glycated hemoglobin level < 8%

Zhang Shuangyuan1, Li Wenjin2, Zhu Li2, Wang Yu2, Wei Zhoudan1, Zhao Jiaoyang1, Chen Yanan1   

  1. 1Shanxi Medical University School of Stomatology•Stomatological Hospital, Taiyuan 030001, Shanxi Province, China; 2Shanxi Medical University School of Stomatology•Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
  • Received:2019-08-13 Revised:2019-08-15 Accepted:2019-09-21 Online:2020-06-08 Published:2020-03-28
  • Contact: Li Wenjin, Associate chief physician, Shanxi Medical University School of Stomatology•Second Hospital of Shanxi Medical University, Taiyyuan 030001, Shanxi Province, China
  • About author:Zhang Shuangyuan, Master candidate, Physician, Shanxi Medical University School of Stomatology•Stomatological Hospital, Taiyuan 030001, Shanxi Province, China
  • Supported by:
    the Shanxi Provincial Returned Overseas Students Research Funding Project, No. 2016-122; the Shanxi Provincial Project Funding for Overseas Returnees, Shanxi Provincial Department of Human Resources and Social Sciences, No. <2017>19

Abstract:

BACKGROUND: When glycated hemoglobin level is < 6%, the efficacy of dental implantation in diabetic patients is not significantly different from that in non-diabetic patients. However, there are few studies on whether the dental implantation success rate in diabetic patients with 6% < glycated hemoglobin level < 8% is decreased.

OBJECTIVE: To evaluate the dental implantation success rate in diabetic patients with 6% < glycated hemoglobin level < 8%.

METHODS: A computer-based retrieval of PubMed, Cochrane library, Embase, CNKI, and Wanfang databases was conducted for the articles published before December 2018. Retrospective and case-control studies comparing the dental implantation success rate between diabetic patients with 6% < glycated hemoglobin level < 8% and non-diabetic patients were retrieved. Data extraction and quality evaluation were performed by two researchers. Meta-analysis was carried out. OR and 95%CI values were used to estimate the success rate of dental implantation in diabetic patients with 6% < glycated hemoglobin level < 8%.

RESULTS AND CONCLUSION: (1) Twelve studies were included, involving 2 698 patients and 9 414 implants. (2) Meta-analysis results showed that there was no significant difference in dental implantation success rate between non-diabetic patients and diabetic patients with 6% < glycated hemoglobin level < 8% [OR=1.13, 95%CI (0.82,1.54). (3) These results suggest that there is no significant difference in dental implantation success rate between diabetic patients with 6% < glycated hemoglobin level < 8% and non-diabetic patients.

Key words: diabetes mellitus, non-diabetes mellitus, dental implant, glycated hemoglobin, success rate, meta-analysis, retrospective studies, case-control studies

CLC Number: