Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (26): 4222-4227.doi: 10.3969/j.issn.2095-4344.2017.26.021
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A novel single-sided groove target release biodegradable stent inhibits coronary artery intimal hyperplasia
Received:
2017-04-15
Online:
2017-09-18
Published:
2017-09-28
About author:
Jin Hui, Associate chief physician, Department of Cardiology, Baotou Central Hospital, Baotou 014040, Inner Mongolia Autonomous Region, China
CLC Number:
Jin Hui, Li Meng.
A novel single-sided groove target release biodegradable stent inhibits coronary artery intimal hyperplasia [J]. Chinese Journal of Tissue Engineering Research, 2017, 21(26): 4222-4227.
2.1 实验动物一般情况 18只小型猪冠状动脉内共植入36枚支架,其中裸支架组中有1只于支架植入中死亡,给予补齐,动物死亡与麻醉剂所致呼吸抑制有关;其余动物均顺利完成手术并进入结果分析,于支架植入后1,3个月时行冠状动脉造影复查。实验观察期内所有存活动物未出现死亡、食欲差、体质量下降等情况。 2.2 冠状动脉造影结果 植入1,3个月,冠状动脉造影显示3组所有支架段冠状动脉均无狭窄发生,支架段血管通畅,支架内未见血栓及动脉瘤等影像学表现。测量结果显示,Firebird 2支架组、Firehawk支架组支架植入1,3个月的管腔丢失均低于裸支架组(P < 0.05),Firebird 2支架组与Firehawk支架组管腔丢失比较差异无显著性意义,见表1。"
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