Effect of SonicFill ultrasonic resin on rat odontoblasts and dental pulp vessels

doi:10.3969/j.issn.2095-4344.2016.16.012

Abstract

Abstract:

BACKGROUND: The mechanical properties of SonicFill ultrasonic resin are better than those of the traditional light-cured composite resin, but its effect on odontoblasts and dental pulp vessels is unclear.

OBJECTIVE: To study the effect of SonicFill ultrasonic resin on odontoblasts and dental pulp vessels of rats using histological methods.

METHODS: Twenty-five Wistar rats are selected for experiment. Ninety-six teeth from the first and second molars were selected and randomly divided into SonicFill ultrasound resin group and Filtek Z350 nano resin group with 48 teeth in each group. Experimental teeth in each group were equally subdivided into 7 days group and 30 days group. Besides, randomly selected five teeth with no intervention served as normal control group. After anesthesia and disinfection, class I cavities on the occlusal surface of the maxillary first and second molars were prepared and filled with SonicFill ultrasound resin and Filtek Z350 nano resin group, respectively. The rats were sacrificed by ink perfusion method, and tooth specimens were taken to observe the changes of odontoblasts and pulp microvessels.

RESULTS AND CONCLUSION: At 7 days after filling, two groups had similar changes in the pulp presenting with mild inflammation. Besides, there were scattered inflammatory cells distributing in the cave pulp tissue, and in most of the specimens, odontoblasts arranged disorderly with little vacuoles and microvascular dilatation in the pulp. At 30 days after filling, in the SonicFill ultrasonic resin group, odontoblasts arranged orderly, inflammatory reaction and microvascular dilatation disappeared basically. In contrast, in the Filtek Z350 nano resin group, disordered odontoblasts decreased, inflammatory reaction weakened, as well as microvascular dilatation became less. These results show that under the experimental condition, both of the SonicFill ultrasonic resin and Filtek SonicFill Z350 nano resin play certain roles in the formation of odontoblasts and dental pulp vessels, but over time all of these effects can automatically disappear.
中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Rats, Wistar, Self-Curing of Dental Resins, Tissue engineering

Zhao Qian-ning, Wang Jian-ping, Tong Wei-wei, Su Dan, Yu Yan-heng . Effect of SonicFill ultrasonic resin on rat odontoblasts and dental pulp vessels[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(16): 2369-2375.

Figures/Tables 5

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