Micro-titanium plate fixation versus suture suspension fixation in cervical posterior expansive open-door laminoplasty: a meta-analysis

doi:10.3969/j.issn.2095-4344.2015.39.028

Abstract

Abstract:

BACKGROUND: Many studies concern the comparison of micro-titanium plate fixation and suture suspension fixation during cervical posterior expansive open-door laminoplasty, but the sample size of many studies has limitations. There is lack of objective evaluation on advantages and disadvantages of micro-titanium plate.
OBJECTIVE: To systemically evaluate the efficacy and safety of micro-titanium plate fixation versus suture suspension fixation in cervical posterior expansive open-door laminoplasty.
METHODS: English and Chinese randomized controlled trials were searched by two reviewers. They retrieved
the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, EMbase, the ISI Web of Knowledge Database, CNKI, CMB, VIP and Wanfang database for randomized controlled trials addressing micro-titanium plate fixation versus suture suspension fixation in cervical posterior expansive open-door laminoplasty published from database foundation to March 1, 2015. The references were also searched by hand. Meta-analyses were performed by using the Rev-Man 5.3 software, provided by the Cochrane Collaboration.
RESULTS AND CONCLUSION: A total of 9 studies involving 642 patients were included. The results of meta-analyses showed that: (1) safety: There were no significant differences between the two groups in operation time [SMD=-0.02, 95%CI (-0.57, 0.54), P=0.95 > 0.05], and intraoperative blood loss [SMD=0.07, 95%CI (-0.26, 0.40), P=0.69 > 0.05]. (2) Efficacy: compared with suture suspension fixation, Japanese Orthopaedic Association Scores were higher [SMD=0.26, 95%CI (0.10, 0.42), P=0.001 < 0.05], the angle of the opened laminae was bigger [SMD=0.25, 95% CI (0.02, 0.48), P=0.04 < 0.05], cervical curvature was better [SMD=0.46, 95% CI (0.27, 0.65), P < 0.000 01], and incidence of axial symptoms was lower [RR=0.40, 95% CI (0.29, 0.56), P < 0.000 01] after micro-titanium plate fixation. These findings suggest that during expansive open-door laminoplasty for treatment of cervical spondylosis, micro-titanium plate fixation and suture suspension fixation can obtain good clinical outcomes. However, Japanese Orthopaedic Association Scores were higher and the angle of the opened laminae was better in micro-titanium plate fixation than in suture suspension fixation. Micro-titanium plate fixation could effectively prevent loss of cervical curvature and reduce the incidence of axial symptoms. For the poor quality of the original studies and small sample size, a prudent choice is suggested. More high-quality large-sample studies are needed for further verification.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Cervical Vertebrae, Internal Fixators, Meta-Analysis, Evidence-Based Medicine

CLC Number:

R318

Ruan Wen-feng, Jin Qi, Liu Hui, Wang Wen-da, Li Jing-feng, Feng Fan, Ping An-song. Micro-titanium plate fixation versus suture suspension fixation in cervical posterior expansive open-door laminoplasty: a meta-analysis[J]. Chinese Journal of Tissue Engineering Research, doi: 10.3969/j.issn.2095-4344.2015.39.028.

Figures/Tables 8

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