Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (53): 8529-8535.doi: 10.3969/j.issn.2095-4344.2014.53.001
Ren Zheng, Liu Xiu-xin, Shen Zhi-min
Revised:
2014-11-12
Online:
2014-12-24
Published:
2014-12-24
About author:
Ren Zheng, Master, Attending physician, Six Affiliated Hospital of Xinjiang Medical University (Six Clinical Medical College of Xinjiang Medical University), Urumqi 830002, Xinjiang Uygur Autonomous Region, China
Supported by:
Science and Technology Project of Tianshan District of Urumqi, No. 20100319
CLC Number:
Ren Zheng, Liu Xiu-xin, Shen Zhi-min. Modified porous pulp core decompression in the treatment of early avascular necrosis of the femoral head: hip replacement rate in 5-year follow-up[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(53): 8529-8535.
2.3 研究终点事件分析 经5年随访后,治疗组57髋,最终28髋行关节置换,髋关节置换率为49%,29例仍未行关节置换,即股骨头生存率为51%;对照组42例髋,其中29例关节置换,髋关节置换率为69%,13例未行置换,即股骨头生存率为31%,经行χ2检验后,P < 0.05,说明治疗组最终髋关节置换率明显低于对照组,差异有显著性意义,见表2。表3表明行髋关节髓芯减压术的患者明显延缓了行关节置换的时间,两组差异有显著性意义(P < 0.05)。对照组治疗后接受髋关节置换的高峰期为治疗后两三年,而治疗组治疗后接受髋关节置换高峰期为术后三四年,说明髓芯减压术确实有效的延缓了患者行髋关节置换的手术时间,两组之间的差异有显著性意义。"
[1] Jones L,Hungerford DS.The pathogenesis of osteonecrosis. Instr Course Lect.2007;56(2):179-196. [2] Mont MA,Jones LC,Hungerford DS.Nontraumatic osteonecrosis of the femoral head:ten years later.J Bone Joint Surg Am.2006;88(7):1117-1132. [3] Ito H,Matsuno T,Omizu N,et al. Mild-term prognosis of nontraumatic Osteonecrosis of the femoral head.J Bone Joint Surg Br.2003;85(6):796-801. [4] Mont MA, Hungerford DS,Maryland MB. Current concept review non traumatic avascular necrosis of the femoral head. J Bone Joint Surg(Am) .1995;77:459. [5] Kim HJ. Autologous adipose tissue-derived stem cells induce persistent bone-like tissue in osteonecrotic femoral heads: not bone-like, but fat-like tissue. Pain Physician. 2012;15: E749- E752. [6] Kaushik AP, Das A, Cui Q. Osteonecrosis of the femoral head: An update in year 2012. World J Orthop.2012;3:49-57. [7] Wikes CH,Visscher MB.Some physiological aspects of bone marropressure.J Bone Joint Surg(Am).1975;57(1):49-57. [8] Henk HJR,Gstettner M,Gress chmldt K,et al.Magnetic resonance imaging and histology of repair in femoral head osteonecresis.Clin Orthop.2001;386(5):42-53. [9] Castro FP,Barraek RL. Core decompression and conservative treatment for avaseular necrosis of the femoral head: a meta analysis.Am J Orthop.2000;29:187-194. [10] Mont MA,Ragland PS,Etienne G. Core decompression of the femoral head for Osteonecrosis using percutaneous multiple small diameter drilling.Clin Orthop Relat Res.2004;429: 131-138. [11] Song WS, Yoo JJ,Kim YM, et al. Results of multiple drilling compared with those of conventional methods of core decompression. Clin Orthop Relat Res.2007;454:139-146. [12] Soohoo NF,Vyas S,Manunga J,et al.Cost-effectiveness analysis of core decompression.J Arthroplasty.2006;21: 670-681. [13] 中华医学会骨科分会显微修复学组及中国修复重建外科专业委员会骨缺损及骨坏死学组.成人股骨头坏死诊疗标准专家共识(2012年版)[J/CD].中华关节外科杂志:电子版,2012,6(3) : 479-484. [14] ARCO(Association Research Circulation Osseous). Committee on Terminology and Classification. ARCO News. 1992;4(1):41-46. [15] Shah NV, Meislin R.Current state and use of biological adhesives in orthopedic surgery . Orthopedics. 2013;36(12): 945-956. [16] Steinberg ME,Larcom PG,Strafford B,et al.Core decompression with bone Grafting for osteonecrosis of the femoral head. Clin Orthop.2001;386 :71-78 [17] 王岩主译.坎贝尔骨科手术学[M].11版.北京:人民军医出版社,2009:832-839 [18] 张鹤山,李子荣.股骨头坏死诊断与治疗的专家建议[J].中华骨科杂志,2007,27(2):146-148. [19] Mont MA,Carbone JJ,Fairbank AC.Core deeompression versus non-operative management for osteoneerosis of the hip.Clin Orthop Relat Res.1996;324:169-178. [20] Zhang G, Qin L, Sheng H ,et al. A novel semisynthesized small molecule icaritin reduces incidence of steroid-associated ostenecrosis with inhibition of both thrombosis and lipid-deposition in a dose-dependent manner. Bone.2009;44:345-356. [21] Lai KA,Shen WJ,Yang CY,et al.The use of alendronate to prevent early collapse Of the femoral head in patients with nontraumatic osteonecrosis a randomized clinical Study.J Bone Joint Surg Am.2005:87:2155-2159. [22] Chen CH, Chang JK, Lai KA, et al. Alendronate in the prevention of collapse of the femoral head in nontraumatic osteonecrosis: a two-year multicenter, prospective, randomized, double-blind, placebo-controlled study. Arthritis Rheum. 2012;64:1572-1578. [23] Peled E, Bejar J, Barak M, et al. Core decompression and alendronate treatment of the osteonecrotic rat femoral head: computer-assisted analysis. Int J Exp Pathol. 2013; 94: 212-216. [24] Glueck CJ,Freiberg RA,Sieve L,et al.Enoxaparin prevents progression of stages I and II osteonecrosis of the hip.Clin Orthop Relat Res.2005:435:164-170. [25] Glueck CJ,Freiberg RA,Sieve L,et al.Enoxaparin prevents progression of stages Ⅰ and Ⅱ osteonecrosis of the hip. Clin Orthop Relat Res.2005;164-170. [26] Camporesi EM, Vezzani G, Bosco G, et al. Hyperbaric oxygen therapy in femoral head necrosis. J Arthroplasty. 2010;25: 118-123. [27] Reis ND,Schwartz O, Militianu D, et al. Hyperbaric oxygen the rapy as a treatment for stage I avascular necrosis of the femoral head. Bone Joint Surg BR.2003;85:371-375. [28] 姜秀芹,王福欣,王培嵩.高压氧治疗股骨头坏死48例临床观察[J].高压氧医学杂志,1996,5:90. [29] Harris WH.Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty.An end-result study using a new method of result evaluation.J Bone Joint Surg Am.1969;51(4):737-755. [30] Koo KH, Kim R. Quantifying the extent of osteonecrosis of the femoral head: a new method using MRI. J Bone Joint Surg (Br).1995; 77: 875-880. [31] Rackwitz L, Eden L, Reppenhagen S, et al. Stem cell- and growth factor-based regenerative therapies for avascular necrosis of the femoral head. Stem Cell Res Ther. 2012;3:7. [32] Helbig L, Simank HG, Kroeber M, et al. Core decompression combined with implantation of a demineralised bone matrix for non-traumatic osteonecrosis of the femoral head.Arch Orthop Trauma Surg. 2012;132:1095-1103. [33] Liu Y, Liu S, Su X. Core decompression and implantation of bone marrow mononuclear cells with porous hydroxylapatite composite filler for the treatment of osteonecrosis of the femoral head. Arch Orthop Trauma Surg.2013;133:125-133. |
[1] | Chen Junming, Yue Chen, He Peilin, Zhang Juntao, Sun Moyuan, Liu Youwen. Hip arthroplasty versus proximal femoral nail antirotation for intertrochanteric fractures in older adults: a meta-analysis [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(9): 1452-1457. |
[2] | Li Zhongfeng, Chen Minghai, Fan Yinuo, Wei Qiushi, He Wei, Chen Zhenqiu. Mechanism of Yougui Yin for steroid-induced femoral head necrosis based on network pharmacology [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(8): 1256-1263. |
[3] | Liu Lihua, Sun Wei, Wang Yunting, Gao Fuqiang, Cheng Liming, Li Zirong, Wang Jiangning. Type L1 steroid-induced osteonecrosis of the femoral head through femoral head and neck junction decompression by fenestration: a single-center prospective clinical study [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(6): 906-911. |
[4] | Liu Zhao, Xu Xilin, Shen Yiwei, Zhang Xiaofeng, Lü Hang, Zhao Jun, Wang Zhengchun, Liu Xuzhuo, Wang Haitao. Guiding role and prospect of staging and classification combined collapse prediction method for osteonecrosis of femoral head [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(6): 929-934. |
[5] | Li Shibin, Lai Yu, Zhou Yi, Liao Jianzhao, Zhang Xiaoyun, Zhang Xuan. Pathogenesis of hormonal osteonecrosis of the femoral head and the target effect of related signaling pathways [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(6): 935-941. |
[6] | Zheng Xiaolong, He Xiaoming, Gong Shuidi, Pang Fengxiang, Yang Fan, He Wei, Liu Shaojun, Wei Qiushi. Bone turnover characteristics in patients with alcohol-induced osteonecrosis of the femoral head [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(5): 657-661. |
[7] | Zeng Xianghong, Liang Bowei. A new strategy for the treatment of osteonecrosis of the femoral head [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(3): 431-437. |
[8] | Cheng Chongjie, Yan Yan, Zhang Qidong, Guo Wanshou. Diagnostic value and accuracy of D-dimer in periprosthetic joint infection: a systematic review and meta-analysis [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(24): 3921-3928. |
[9] | Fu Panfeng, Shang Wei, Kang Zhe, Deng Yu, Zhu Shaobo. Efficacy of anterolateral minimally invasive approach versus traditional posterolateral approach in total hip arthroplasty: a meta-analysis [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(21): 3409-3415. |
[10] | Wang Yan, Dong Benchao, Wang Ying, Sun Lei, Lu Bin, Bai Haohao, Tian Aixian, Ma Jianxiong, Ma Xinlong. Animal models of osteonecrosis of the femoral head: modeling methods and characteristics [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(2): 292-297. |
[11] | Song Kaikai, Du Gangqiang, Li Peng, Jiang Shengyuan, Gong Zhihao, Zhang Zhiwei, Zhang Kai . Application of head-neck ratio in the treatment of femoral neck fracture in aged patients with artificial femoral head replacement [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(18): 2805-2809. |
[12] | Yang Kun, Fei Chen, Wang Pengfei, Zhang Binfei, Yang Na, Tian Ding, Zhuang Yan, Zhang Kun . Meta-analysis of the efficacy of robot-assisted and traditional manual implantation of cannulated screws in the treatment of femoral neck fracture [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(18): 2938-2944. |
[13] | Zhou Yi, Chen Yueping, Zhang Xiaoyun, Lai Yu, Liao Jianzhao, Li Shibin. An exploration on mechanism of Shengyu Decoction in treating osteonecrosis of the femoral head based on network pharmacology [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(17): 2687-2696. |
[14] | Huang Na, Liu Jiayue, Huang Yingjie, Wen Junmao, Wang Haibin, Zhang Qingwen, Zhou Chi . Bibliometric and visualized analysis of research on osteonecrosis of the femoral head from the Web of Science in the last 5 years [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(17): 2711-2718. |
[15] | Xin Pengfei, Ke Mengnan, Zhang Haitao, Urishana, Li Ziqi, Zhuang Zhikun, Wei Qiushi, He Wei. Common mechanism of Chinese herbs for promoting blood circulation and removing blood stasis in the treatment of osteonecrosis of the femoral head: an analysis based on network pharmacology [J]. Chinese Journal of Tissue Engineering Research, 2021, 25(17): 2727-2733. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||