Bibliometric and visualized analysis of research on osteonecrosis of the femoral head from the Web of Science in the last 5 years

doi:10.3969/j.issn.2095-4344.3195

Abstract

Abstract: BACKGROUND: Studies have indicated that femoral head necrosis is a refractory disease in orthopedics. To explore the research status and research focus in the field of osteonecrosis of the femoral head is beneficial to grasp the research direction, promote the development of the field of femoral head necrosis, and make it better serve the clinical practice.
OBJECTIVE: To explore the development of research hotspots on osteonecrosis of the femoral head in the past 5 years and predict the future research focus in this field, and to provide reference for relevant researchers.
METHODS: Base on the Science Citation Index Extended database of the Web of Science database, we search for literature on osteonecrosis of the femoral head from 2016 to 2020 with the theme of "osteonecrosis of the femoral head,” and the VOSviewer software was applied for visualization analysis, including keyword co-occurrence analysis, co-author analysis, institutional co-authoring analysis, country co-authoring analysis, and co-citation analysis.
RESULTS AND CONCLUSION: Based on keyword co-occurrence analysis, current research on osteonecrosis of the femoral head is divided into four main categories: risk factors, diagnose and treatment, orthormorphia, cell biology, genetics heredity of osteonecrosis of the femoral head. Steriod-induced osteonecrosis of the femoral head, bone marrow mesenchymal stem cells, and osteogenic differentiation are recent research hotspots in the field of osteonecrosis of the femoral head. However, the pathogenesis and treatment methods of steroid-induced osteonecrosis of the femoral head have not yet been clarified, and the mechanism of action and therapeutic effects of mesenchymal stem cells are still unclear. Therefore, it is speculated that further excavation of the mechanism of femoral head necrosis and improvement of its treatment are important research contents in the future. To conclude, the mechanism of steroid-induced osteonecrosis of the femoral head and the therapy of bone marrow mesenchymal stem cells for osteonecrosis of the femoral head will be studied deeply around the process of osteogenic differentiation.

Key words: bone, femoral head, stem cell">, steroid">, osteogenesis">, differentiation">, bibliometrics">, visualization analysis

CLC Number:

Huang Na, Liu Jiayue, Huang Yingjie, Wen Junmao, Wang Haibin, Zhang Qingwen, Zhou Chi . Bibliometric and visualized analysis of research on osteonecrosis of the femoral head from the Web of Science in the last 5 years[J]. Chinese Journal of Tissue Engineering Research, 2021, 25(17): 2711-2718.

Figures/Tables 15

References

[1] 中华医学会骨科分会显微修复学组及中国修复重建外科专业委员会骨缺损及骨坏死学组.成人股骨头坏死诊疗标准专家共识(2012年版)[J].中国骨与关节外科,2012,5(2):185-192.
[2] 李子荣.股骨头坏死临床诊疗规范[J].中国矫形外科杂志,2016, 24(1):49-54.
[3] 王宏伟,崔文芳,冯雪亮,等.髓芯减压微创植骨术与全髋关节置换术治疗缺血性股骨头坏死的中期预后比较[J].临床合理用药杂志,2016,9(4):140-141.
[4] 洪志楠,何伟,魏秋实,等.股骨头坏死物理治疗的研究进展[J].中国矫形外科杂志,2017,25(23):2160-2164.
[5] 芶开来,李明.中医药治疗股骨头坏死研究[J].医学信息,2020, 33(3):59-62.
[6] 邓云平,李伟.股骨头坏死早期治疗方法研究进展[J].西部医学, 2017,29(2):292-296.
[7] 李聪聪,叶国柱,刘文刚,等.股骨头坏死的手术及西药治疗现状[J].中医正骨,2020,32(1):43-46, 55.
[8] 朱善邦,冯新哲,徐卫东.2009-2018年强直性脊柱炎研究现状的文献计量学分析[J].第二军医大学学报,2020,41(4):455-460.
[9] 韩涛,谢雁鸣,刘峘.仙灵骨葆胶囊治疗骨性关节炎文献计量学分析[J].亚太传统医药,2019,15(1):161-164.
[10] 吴玖斌,李蒙,谢雁鸣,等.膝关节骨性关节炎当代中医学术团队研究[J].北京中医药大学学报,2016,39(6):516-519.
[11] XING D, ZHAO Y, DONG S, et al. Global research trends in stem cells for osteoarthritis: a bibliometric and visualized study. Int J Rheum Dis. 2018;21(7):1372-1384.
[12] HIRSCH JE. An index to quantify an individual’s scientific research output. Proc Natl Acad Sci U S A. 2005;102(46):16569-16572.
[13] 唐晓娜,曾瑶,陈阳阳,等.基于Web of Science数据库中风病护理的文献计量学分析[J].广西医学,2020,42(7):908-913, 917.
[14] 沈莹姗,龚水帝,何晓铭,等.文献计量学与可视化分析法评估Perthes病的研究现状与发展趋势[J].中国组织工程研究,2019, 23(28):4503-4509.
[15] VAN ECK NJ, WALTMAN L. Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics. 2010;84(2): 523-538.
[16] 张强,朱婵.近5年骨质疏松英文文献的计量学及可视化分析:Web of Science来源数据[J].中国组织工程研究,2020,24(17):2752-2758.
[17] 何晓铭,龚水帝,郑小龙,等.应用文献计量学与可视化分析探讨骨与关节结核的全球研究现状及发展趋势[J].中国组织工程研究, 2020,24(20):3234-3239.
[18] 谢庆华,林玉芬.林玉芬教授运用温通法治疗股骨头坏死经验[J].风湿病与关节炎,2020,9(1):39-41.
[19] 李俊良.科研合作网络特征分析及比较—以我国“双一流”大学与美国知名大学为例[J].情报探索,2020(4):35-43.
[20] 魏凤鸣,陈飙.我国科研机构合作现状及其影响因素分析[J].科技视界,2018(29):14-18.
[21] 杜建,张玢,李阳.我国医学领域不同学科作者合作度与论文影响力的关系[J].中华医学图书情报杂志,2012,21(3):18-23.
[22] MONT MA, CHERIAN JJ, SIERRA RJ, et al. Nontraumatic osteonecrosis of the femoral head: where do we stand today? A ten-year update. J Bone Joint Surg Am. 2015;97(19):1604-1627.
[23] MONT MA, HUNGERFORD DS. Non-traumatic avascular necrosis of the femoral head. J Bone Joint Surg Am. 1995;77(3):459-474.
[24] MONT MA, JONES LC, HUNGERFORD DS. Nontraumatic osteonecrosis of the femoral head: ten years later. J Bone Joint Surg Am. 2006;88(5): 1117-1132.
[25] WANG A, REN M, WANG J. The pathogenesis of steroid-induced osteonecrosis of the femoral head: a systematic review of the literature. Gene. 2018;671:103-109.
[26] HUA KC, YANG XG, FENG JT, et al. The efficacy and safety of core decompression for the treatment of femoral head necrosis: a systematic review and meta-analysis. J Orthop Surg Res. 2019;14(1):306.
[27] LEE YJ, CUI Q, KOO KH. Is There a role of pharmacological treatments in the prevention or treatment of osteonecrosis of the femoral head? A systematic review. J Bone Metab. 2019;26(1):13-18.
[28] SULTAN AA, KHLOPAS A, SURACE P, et al. The use of non-vascularized bone grafts to treat osteonecrosis of the femoral head: indications, techniques, and outcomes. Int Orthop. 2019;43(6):1315-1320.
[29] WANG XY, GONG LJ, HUANG JM, et al. Pinocembrin alleviates glucocorticoid-induced apoptosis by activating autophagy via suppressing the PI3K/Akt/mTOR pathway in osteocytes. Eur J Pharmacol. 2020;880:173212.
[30] WU X, SUN W, TAN M. Noncoding RNAs in Steroid-Induced Osteonecrosis of the Femoral Head. Biomed Res Int. 2019;2019: 8140595.
[31] WANG Y, MA X, CHAI W, et al. Multiscale Stem Cell Technologies for Osteonecrosis of the Femoral Head. Stem Cells Int. 2019;2019:8914569.
[32] LI J, GE Z, JI W, et al. The Proosteogenic and proangiogenic effects of small extracellular vesicles derived from bone marrow mesenchymal stem cells are attenuated in steroid-induced osteonecrosis of the femoral head. Biomed Res Int. 2020;2020:4176926.
[33] WANG T, TENG S, ZHANG Y, et al. Role of mesenchymal stem cells on differentiation in steroid-induced avascular necrosis of the femoral head. Exp Ther Med. 2017;13(2):669-675.
[34] HUANG W, JIN S, YANG W, et al. Agrimonia pilosa polysaccharide and its sulfate derives facilitate cell proliferation and osteogenic differentiation of MC3T3-E1 cells by targeting miR-107. Int J Biol Macromol. 2020;157: 616-625.
[35] HUANG XZ, HUANG J, LI WZ, et al. LncRNA-MALAT1 promotes osteogenic differentiation through regulating ATF4 by sponging miR-214: Implication of steroid-induced avascular necrosis of the femoral head. Steroids. 2020;154:108533.
[36] LIU G, LUO G, BO Z, et al. Impaired osteogenic differentiation associated with connexin43/microRNA-206 in steroid-induced avascular necrosis of the femoral head. Exp Mol Pathol. 2016;101(1):89-99.
[37] WEN Q, ZHOU C, LUO W, et al. Pro-osteogenic effects of fibrin glue in treatment of avascular necrosis of the femoral head in vivo by hepatocyte growth factor-transgenic mesenchymal stem cells. J Transl Med. 2014;12:114.
[38] CHEN YP, CHEN WC, WANG KC, et al. Effectiveness of synovial fluid mesenchymal stem cells embedded in alginate beads for treatment of steroid-induced avascular necrosis of the femoral head. J Orthop Sci. 2014;19(4):657-666.