Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (48): 7844-7848.doi: 10.3969/j.issn.2095-4344.2014.48.024

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Application of three-dimensional models constructed using virtual simulation 
technique in the vertebral metastatic tumor

Liu Deng-jun1, He Xiao-bing1, Wang Ming-gui1, Li Zheng-yan1, Li Qi2, Lin Li-jun2   

  1. 1Department of Orthopedics, Chongqing Fuling Central Hospital, Chongqing 408000, China; 2Department of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou 510282, Guangdong Province, China
  • Online:2014-11-26 Published:2014-11-26
  • Contact: Liu Deng-jun, Department of Orthopedics, Chongqing Fuling Central Hospital, Chongqing 408000, China
  • About author:Liu Deng-jun, Attending physician, Department of Orthopedics, Chongqing Fuling Central Hospital, Chongqing 408000, China

Abstract:

BACKGROUND: Vertebral metastatic tumor often damages vertebral body and the appendix, and causes severe pain in patients and high incidence of complications, such as paraplegia and spinal kyphosis. The principle of metastatic tumor treatment is early diagnosis, complete surgical resection, and postoperative chemotherapy. Imaging techniques such as CT can detect spinal metastases and accurately position the tumor before surgery. Currently visualized simulation and virtual reality techniques have been increasingly used in the field of orthopedics.
OBJECTIVE: To find an anterior-posterior approach for the treatment of vertebral metastases using visual reality technique.
METHODS: Based on the 64-layer spiral CT two-dimensional images of lumbar vertebra, we reconstructed the structure of normal vertebrae, affected vertebrae, abdominal aorta and bilateral kidney three-dimensionally using Mimics software. Then anterior debridement, titanium bone cement supporting, and posterior pedicle screw fixation were performed on three-dimensional models.
RESULTS AND CONCLUSION: Three-dimensionally reconstructed models were clearly visible in Dicom format, and can reproduce the structure of affected vertebrae and adjacent organs. The virtual stimulation operation provided clarity with strong relief perception. Virtual simulation surgery accurately visualize three-dimensional structure of malignant tumor and adjacent structure, position the lesion site, and reconstruct spinal sequence via the posterior approach. This method provides an objective evidence for individualized treatment programs.


中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程


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Key words: tissue engineering, lumbar vertebrae, malignant tumor, vertebral column

CLC Number: