Gastrointestinal function recovery influences the prognosis of patients after liver transplantation

doi:10.3969/j.issn.2095-4344.2013.31.003

Abstract

Abstract:

BACKGROUND: Delayed gastrointestinal function recovery often appears in patients after liver transplantation. It may influence patient’s prognosis.
OBJECTIVE: To retrospectively analyze the recovery time of gastrointestinal function in patients after liver transplantation, and to explore the influence of the gastrointestinal function recovery after liver transplantation on the prognosis.
METHODS: The data of 254 liver transplantation patients selected from two hospitals of Fujian province from January 2006 to October 2011 were collected. The recovery time of gastrointestinal function in liver transplantation patients was descriptively analyzed. This study was divided into three groups (< 7 days group, 7-14 days group and >14 days group) according to the recovery time in order to comparatively observe the incidence of postoperative complications, hospital stay and costs in hospital.
RESULTS AND CONCLUSION: Among the 254 cases, 142 cases had the full recovery of gastrointestinal function for < 7 days, 90 cases 7-14 days, and 22 cases for > 14 days. The patients in the < 7 days group had the lowest incidence of complications (lung, abdominal cavity and incision), 2 weeks postoperative serum albumin level, hospital stay and cost when compared with other two groups, followed by the 7-14 days group, and highest in the >14 days group (P < 0.05); the 2 weeks postoperative serum albumin level was highest in the < 7 days group, followed by 7-14 days group, and lowest in the > 14 days group (P < 0.05); there were no significant differences in the renal dysfunction after liver transplantation and the incidence of acute rejection (P > 0.05). Higher incidence for patients after liver transplantation with delayed gastrointestinal function recovery may result in higher incidence of postoperative infection complications, longer hospital stay and higher hospital costs.

Key words: organ transplantation, liver transplantation, gastrointestinal function recovery, liver function, total bilirubin, albumin, complication, lung bacterial infection, abdominal infection, infection

CLC Number:

R318

Wang Xu, Yan Cheng-mei. Gastrointestinal function recovery influences the prognosis of patients after liver transplantation[J]. Chinese Journal of Tissue Engineering Research, doi: 10.3969/j.issn.2095-4344.2013.31.003.

Figures/Tables 3

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