Chinese Journal of Tissue Engineering Research ›› 2013, Vol. 17 ›› Issue (12): 2116-2122.doi: 10.3969/j.issn.2095-4344.2013.12.004

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Staged injection of bone cement in percutaneous vertebroplasty

Zeng Yi-wen, Xu Jian-an   

  1. Nanjing University of Chinese Medicine, Nanjing 21000, Jiangsu Province, China
  • Received:2012-07-14 Revised:2012-08-15 Online:2013-03-19 Published:2013-03-19
  • About author:Zeng Yi-wen☆, Studying for doctorate, Chief physician, Nanjing University of Chinese Medicine, Nanjing 21000, Jiangsu Province, China zenyiwen@163.com

Abstract:

BACKGROUND: Percutaneous vertebroplasty can induce bone cement leakage to oppress and damage the surrounding nerves, spinal cord and vascular tissues in osteoporotic vertebral compression fractures patients who have incomplete vertebral bone cortex.
OBJECTIVE: To observe the method and therapeutic effect of staged injection of bone cement in percutaneous vertebroplasty.
METHODS: Twenty-six patients with osteoporotic vertebral compression fractures, who had incomplete vertebral bone cortex, underwent percutaneous vertebroplasty. Of the 26 patients, 12 received unilateral transpedicular injection and 14 were administered with bilateral transpedicular injection of bone cement. The fractured vertebra reduction, vertebral volume, distribution and leakage of bone cement and visual analogue scale scoring were observed before and after operation.
RESULTS AND CONCLUSION: All the operations were successful, with no leakage of bone cement, damage of nerve root or spinal cord, pulmonary embolism, and acute cardiovascular system response. None of patients died during the operation. After 6 months, vertebral volume and scores on visual analogue scale were improved significantly (P < 0.01). However, no difference in the vertebral volume and visual analogue scale scores was found between the two groups (P > 0.01). As described above, staged injection of bone cement increases the surgical indications for percutaneous vertebroplasty, avoid the leakage of bone cement effectively and get satisfactory clinical curative effect.

Key words: biomaterials, tissue-engineered bone materials, bone cement, leakage, percutaneous vertebroplasty, osteoporotic vertebral compression fractures, staged injection, indications, cortical bone, vertebra reduction, biomaterial photographs-containing paper

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