Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (16): 2466-2471.doi: 10.3969/j.issn.2095-4344.3101

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Bone cement distribution of percutaneous curved vertebroplasty for the treatment of osteoporotic vertebral compression fractures

Li Qiang, Li Jun, Luan Jian, Jin Canghai, Hao Meng, Lin Yong   

  1. East Branch, Qingdao Municipal Hospital, Qingdao 266000, Shandong Province, China 
  • Received:2020-05-08 Revised:2020-05-13 Accepted:2020-06-12 Online:2021-06-08 Published:2021-01-07
  • Contact: Lin Yong, Associate Professor, Master’s supervisor, East Branch, Qingdao Municipal Hospital, Qingdao 266000, Shandong Province, China
  • About author:Li Qiang, MD, Associate chief physician, East Branch, Qingdao Municipal Hospital, Qingdao 266000, Shandong Province, China

Abstract: BACKGROUND: Percutaneous curved vertebroplasty is a new method for the treatment of osteoporotic vertebral compression fractures, which can achieve a good therapeutic effect, while the distribution of bone cement has not been explored thoroughly.
OBJECTIVE: To retrospectively analyze the therapeutic effect of percutaneous curved vertebroplasty and the distribution characteristics of bone cement in the treatment of osteoporotic vertebral compression fractures.
METHODS: A total of 28 patients with osteoporotic vertebral compression fractures of a single thoracic or lumbar vertebrate, who were admitted to Qingdao Municipal Hospital from June 2017 to February 2018, including 2 males and 26 females, aged 62-86 years old, underwent percutaneous curved vertebroplasty and were retrospectively reviewed. The bone cement was injected at the puncture side, the middle of the vertebrate and the contralateral side respectively. The change of anterior vertebral body height of the injured vertebrae and the leakage of bone cement postoperatively were observed according to X-ray images preoperatively, 48 hours and 6 months postoperatively. The bone cement distribution within the vertebrate was observed by CT scanning. Visual analogue scale score and Oswestry disability index were recorded for the evaluation of recovery. All protocols were approved by the Ethical Committee of Qingdao Municipal Hospital.
RESULTS AND CONCLUSION: (1) There were 6 out of 28 cases of bone cement leakage, including 4 cases of paravertebral leakage and 2 cases of intervertebral space leakage, and no clinical symptoms were observed in all the 6 cases. CT scanning showed that the bone cement was mainly distributed in the anterior 2/3 of the vertebral body. The maximum distribution area of bone cement was (4.5±0.9) cm2, with the contralateral area (2.0±0.5) cm2 and the puncture side area (2.5±0.7) cm2, which makes the ratio of the puncture side area versus contralateral area 0.85±0.27. (2) The anterior vertebral body heights preoperatively showed no significant difference than those postoperatively in 28 patients (P > 0.05). (3) The visual analogue scale score and Oswestry disability index 48 hours and 6 months postoperatively were both significantly different from those before operation (P < 0.05). (4) The results showed that percutaneous curved vertebroplasty treatment of osteoporotic vertebral compression fractures has the advantages of accurate surgical effects and even distribution of bone cement.

Key words: bone, materials, bone cement, vertebroplasty, osteoporosis, vertebral compression fracture, Oswestry disability index

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