Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (36): 6834-6840.doi: 10.3969/j.issn.2095-4344.2012.36.033

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Stem cells transplantation in the treatment of diabetes

Chen Guo-chang1, Wang Xi-ran2   

  1. 1Affiliated Beijing Obstetrics and Gynecology Hospital of Capital Medical University, Beijing 100006, China;
    2Second Artillery General Hospital, Beijing 100088, China
  • Received:2012-03-29 Revised:2012-08-20 Online:2012-09-02 Published:2012-09-02
  • About author:Chen Guo-chang★, Master, Associate chief physician, Affiliated Beijing Obstetrics and Gynecology Hospital of Capital Medical University, Beijing 100026, China chen3260@126.com

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Abstract:

BACKGROUND: Diabetes is a specific autoimmune disease for pancreatic β cell; it can be treated by pancreas transplantation or islet transplantation, but due to the donor and the rejection, the clinical application is limited.
OBJECTIVE: To multi-level explore the development trends of the researches on stem cells transplantation for the treatment of diabetes.
METHODS: The articles on stem cells transplantation for the treatment of diabetes were selected in the CNKI database and Web of Science database from 2002 to 2011, and the analysis capabilities of the database and Excel software chart function were used to analyze the data characteristics. The articles on the stem cells transplantation for the treatment of diabetes in the CNKI database were analyzed.
RESULTS AND CONCLUSION: A total of 128 articles on stem cells transplantation for the treatment of diabetes were selected from the CNKI database, and 725 articles were searched from the Web of Science database, and the number of the articles was in the increasing trend. The articles in the CNKI database are mainly about the bone marrow mesenchymal stem cells, pancreatic stem cells and hematopoietic stem cells. The categories of the articles are mainly the endocrine metabolic classification. The number of the articles in the Web of Science database is larger than that in the CNKI database, and most of the articles were published by US. The National Natural Science Foundation of China plays an important role in the research on stem cells transplantation for the treatment of diabetes.

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