Chinese Journal of Tissue Engineering Research ›› 2019, Vol. 23 ›› Issue (26): 4260-4264.doi: 10.3969/j.issn.2095-4344.1303

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Soft silicone foam dressing for the treatment of radiation dermatitis: a meta-analysis

Shen Qian1, Qiu Wenbo2, Hu Peixin2, Li Chun2, Zhou Chunjiao1, Chen Juan1
  

  1. Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, Guangdong Province, China; School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong Province, China
  • Received:2019-03-26
  • Contact: Chen Juan, Associate chief nurse, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, Guangdong Province, China
  • About author:Shen Qian, Master candidate, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, Guangdong Province, China
  • Supported by:

    Special Fund for Research on Traditional Chinese Medicine Science and Technology in Guangdong Provincial Hospital of Traditional Chinese Medicine, No. YN2018YY07 (to CJ)

Abstract:

BACKGROUND: Soft silicone foam dressing is made up of 3 layers: soft silicone wound contact layer, polyurethane foam absorbing layer and breathable and waterproof outer covering film. It not only facilitates granulation tissue growth, but also provides a good wet environment for wound healing.
OBJECTIVE: To evaluate the efficacy of soft silicone foam dressing in the treatment of radiation dermatitis.
METHODS: Randomized controlled trials regarding soft silicone foam dressing applied to radiation dermatitis were searched by computer in PubMed, EMBASE, Cochrane, China Academic Journals Full-text Database, Chinese Biomedical Literature Database, Wanfang database and Chinese Science and Technology Periodicals Database.The retrieval time was limited to the period from database foundation to October 2018. Literature screening, quality evaluation and data extraction were conducted independently by two postgraduates. Revman 5.3 software was used for data analysis.
RESULTS AND CONCLUSION: Six Chinese literatures were included, including 416 patients with radiation dermatitis. The experimental group was treated with soft silicone foam dressing, while the control group was treated with traditional dressing, moist exposed burn ointment or lanolin ointment. Meta-analysis results showed that the healing time of radiation dermatitis in the experimental group was shorter than that in the control group [MD=-6.36, 95%CI (-8.72, -4.00), Z=5.28, P < 0.000 01]. The healing rate of radiation dermatitis in the experimental group was significantly higher than that in the control group [OR=5.67, 95%CI (1.74, 18.41), Z=2.89, P=0.004]. The results suggest that soft silicone foam dressing exhibits better therapeutic effects on radiation dermatitis than other dressings.

Key words: soft silicone foam dressing, wound healing, traditional dressing, moist exposed burn ointment, lanolin ointment, radiation dermatitis, randomized controlled trial, meta-analysis

CLC Number: