Establishment of finite element model of L4-5 and mechanical analysis of degenerative intervertebral discs

doi:10.3969/j.issn.2095-4344.1083

Abstract

Abstract:

BACKGROUND: Spine plays a connecting link role in the human body. The gravity of the upper part of the trunk is transmitted to the lumbosacral region until the pelvis. L₄_-₅ vertebral body is at the lowermost end of the spine, and the load is the largest. The intervertebral disc is also subjected to considerable high stress, so the intervertebral disc is prone to degeneration and herniation.

OBJECTIVE: To establish a finite element model of human L₄_-₅ vertebral body and intervertebral disc, and to conduct mechanical simulation analysis of degenerative disc.

METHODS: The lumbar spine of adult women was scanned by GE64 spiral CT, and 206 CT DICOM images of 2 mm in thickness were obtained. Three-dimensional reconstruction of the vertebral body was performed with Mimics software. Then 3-matic software was used to establish the intervertebral disc, to divide surface mesh and volume mesh, and then models were imported the Mimics software in CDB format to give vertebral body and intervertebral disc material properties, and finally imported inte Ansys software to establish ligaments for biomechanical analysis of L₄_-₅ vertebrae and intervertebral disc.

RESULTS AND CONCLUSION: (1) The finite element model for the mechanical analysis of the lumbar vertebral body and the degenerated intervertebral disc was successfully established. (2) The standing force of the anterior disc was higher than that of the posterior part (F=7.995, P < 0.000 1). The nucleus in the middle of the intervertebral disc was subjected to the load compared with the anterior annulus. The anterior annulus was low (t=5.013, P < 0.000 1). (3) In summary, in the finite element model of the L₄_-₅ vertebral body, the nucleus pulposus and the posterior disc herniation and the anterior annulus fibrosus are subjected to high stress and the posterior nucleus pulposus and posterior annulus fibrosus are transmitted from the biomechanical point of view. The compression of the nucleus and posterior annulus is closely related to the degeneration of the intervertebral disc.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Lumbar Vertebrae, Intervertebral Disk, Biomechanics, Tissue Engineering

CLC Number:

R445

Wen Yi, Su Feng, Liu Su, Zong Zhiguo, Zhang Xin, Ma Pengpeng, Li Yuexuan, Li Rui, Zhang Zhimin. Establishment of finite element model of L₄_-₅ and mechanical analysis of degenerative intervertebral discs

[J]. Chinese Journal of Tissue Engineering Research, 2019, 23(8): 1222-1227.

Figures/Tables 4

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Establishment of finite element model of L₄_-₅ and mechanical analysis of degenerative intervertebral discs

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