Imaging changes of idiopathic scoliosis treated with bone morphogenetic protein 2 nanometer artificial bone implantation combined with chiropractic manipulation

doi:10.3969/j.issn.2095-4344.0926

Abstract

Abstract:

BACKGROUND: In recent years, chiropractic manipulation with bone morphogenetic protein 2 nanometer artificial bone has achieved ideal outcomes in idiopathic scoliosis patients. However, this conclusion needs to be further verified.

OBJECTIVE: To investigate the effect and imaging features of chiropractic manipulation combined with bone morphogenetic protein 2 nanometer artificial bone implantation in patients with idiopathic scoliosis.

METHODS: Eighty Idiopathic scoliosis children aged 9-16 years were divided into two groups. The control group (n=40) was treated with chiropractic manipulation. The treatment group (n=40) was treated with chiropractic manipulation combined with bone morphogenesis protein 2 nanometer artificial bone implantation. Chiropractic treatment was performed once every other day. Three months after treatment, X-ray was used to assess the Cobb angle of scoliosis and visual analogue scale was used to evaluate the pain.

RESULTS AND CONCLUSION: (1) The visual analogue scale score and the Cobb angle of scoliosis were lower in both groups at 3 months after treatment than the baseline (P < 0.05). (2) At 3 months after treatment, the curative effect of treatment group was higher than that of control group (90% vs. 73 %, P < 0.05). The Cobb angles of the lumbar and thoracic vertebrae in the treatment group at 3 months after treatment were significantly lower than those of the control group [thoracic vertebrae (17.32±3.98)° vs. (19.27±4.23)°; lumbar vertebrae (18.21±3.12)° vs. (23.25±4.64)°, P < 0.05]. The visual analogue scale scores in the treatment group were significantly lower than those in the control group at 1, 2 and 3 months after treatment [treatment group (3.51±1.02), (1.15±0.57), (0.99±0.12) points; control group (5.01±1.31), (3.57±0.95) and (1.46±0.64) points, respectively; P < 0.05]. These findings suggest that the bone morphogenetic protein 2 nanometer artificial bone implantation combined with chiropractic manipulation can improve spinal function and relieve pain in patients with idiopathic scoliosis.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Manipulation, Spinal, Bone Morphogenetic Proteins, Kyphosis, Tissue Engineering

CLC Number:

R318

Li Lian-tai, Hu Hua, Wang Shu-jun, Xie Shuang-xi, Wang Jun-bo, Wang Li-xin. Imaging changes of idiopathic scoliosis treated with bone morphogenetic protein 2 nanometer artificial bone implantation combined with chiropractic manipulation[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(26): 4139-4143.

Figures/Tables 5

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