Gender and implant fixation affect the healing of alcohol-inactivated bone

doi:10.3969/j.issn.2095-4344.0554

Abstract

Abstract:

BACKGROUND: Alcohol inactivated replantation is widely used in the treatment of malignant bone tumors, but the postoperative bone healing is little reported.

OBJECTIVE: To analyze the related factors affecting the bone healing of the autograft bone after alcohol inactivated replantation.

METHODS: Twenty-one patients with malignant bone tumor who received alcohol-inactivated autograft bone replantation were enrolled, including 8 males and 13 females with an age of 7-56 years. Among which, 17 cases underwent plate-screw internal fixation, and 4 cases received intramedullary nailing fixation. All patients were followed up to observe the bone healing. The related factors of the autograft bone healing were analyzed.

RESULTS AND CONCLUSION: (1) The follow-up time was 2-6 years, with an average of 3.8 years. (2) Eleven patients (1 male and 10 females, with an average age of 20.8 years) achieved bone union, the average length of autograft bone was 17.36 cm, all fixed using plates, and the average healing time was 20 months. (3) Bone nonunion occurred in 10 patients (7 males and 3 females, with an average age of 20.5 years), the average length of autograft bone was 16.10 cm, 4 cases of intramedullary nailing fixation, and 6 cases of plate-screw fixation. (4) The differences in the average age and average length of autograft bone were insignificant between two groups. The sex and internal fixation ways showed significant differences between two groups (P < 0.05). (5) These results suggest that the age and the length of the autograft bone have no significant effect on autograft bone healing. The female patients and plate-screw internal fixation are beneficial for bone healing after alcohol inactivated replantation.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Bone Neoplasms, Tissue Engineering

CLC Number:

R318

Tian Zhi-chao, Gu Zhi-yuan, Wang Xin, Liu Zhi-yong, Yao Wei-tao, Wang Jia-qiang, Zhang Peng, Cai Qi-qing, Ge Hong. Gender and implant fixation affect the healing of alcohol-inactivated bone [J]. Chinese Journal of Tissue Engineering Research, 2018, 22(31): 4931-4936.

Figures/Tables 2

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