Peek Prevail anterior cervical interbody fusion for herniation of cervical intervertebral disc: a 12-month follow-up

doi:10.3969/j.issn.2095-4344.0351

Abstract

Abstract:

BACKGROUND: Treatment outcomes of anterior cervical discectomy and fusion (ACDF) for cervical spondylosis are confirmed. The use of anterior plates increases fusion rates but may be associated with high rates of postoperative dysphagia and adjacent segment degeneration. A new Peek Prevail interbody device is designed to provide stability during spinal fusion.

OBJECTIVE: To analyze the short-period clinical outcome of the Peek Prevail anterior cervical interbody fusion for cervical spondylosis.

METHODS: From August 2014 to May 2015, 31 patients with cervical spondylosis implanted with Peek Prevail cervical interbody device in ACDF procedure were included. All patients underwent single-segmental fusion. The Visual Analogue Scale, Japanese Orthopaedic Association and neck disability index were assessed at baseline and postoperatively. The incidence of postoperative dysphagia was evaluated using Bazaz dysphagia index. The signal strength of the adjacent intervertebral disc and adjacent paraspinal muscle was measured on MRI, and signal-noise ratio was calculated to assess the degeneration of adjacent intervertebral disc at baseline and 1 year postoperatively. Cervical X-ray examination was regularly reviewed, the short-term efficacy was evaluated by observing the intervertebral space and cage loosening and subsidence.

RESULTS AND CONCLUSION: (1) All 31 patients were followed up for 12-15 months. (2) The average operation time was (63.0±12.5) minutes and average intraoperative blood loss was (25.0+7.4) mL. There were three (mild in two and medium in one patient) patients complaining of dysphagia at 2 days post-operation. All the symptoms of three cases disappeared after symptomatic treatment within 2 weeks. (3) All patients had a satisfactory improvement of neurologic outcome. The Visual Analogue Scale scores were decreased from 8.2±1.5 preoperatively to 2.4±1.2 at 12 months postoperatively (P < 0.05). The Japanese Orthopaedic Association scores at baseline and postoperative 12 months were 9.5±2.2 and 16.7±1.1 (P < 0.05). The neck disability index was improved from 44.2±3.4 preoperatively to 11.3±1.0 at 12 months postoperatively (P < 0.05). The signal-noise ratio of adjacent intervertebral disc at baseline and 12 months postoperatively was 20.3±2.1 and 19.1±1.8 (P > 0.05). (4) There were no complications such as cage and screw loosening, shifting and subsidence. (5) The results suggest that the Peek Prevail interbody fusion system is reliable and efficient for herniation of cervical intervertebral disc. The incidence of postoperative dysphagia is low, cannot accelerate the degeneration of adjacent intervertebral discs and short-term clinical results are satisfactory.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Spinal Fusion, Intervertebral Disk Displacement, Tissue Engineering

CLC Number:

R318

Li Guo, He Yue, Gu Zu-chao, Zhang Yu, Liu Jin. Peek Prevail anterior cervical interbody fusion for herniation of cervical intervertebral disc: a 12-month follow-up[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(27): 4348-4353.

Figures/Tables 2

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