Chinese Journal of Tissue Engineering Research ›› 2018, Vol. 22 ›› Issue (12): 1962-1968.doi: 10.3969/j.issn.2095-4344.0214

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Acupuncture treatment for urinary retention following spinal cord injury: a Meta-analysis

Cheng Jie1, Guo Jia-bao2, Chen Bing-lin3, Zhu Yi4   

  1. 1Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, China; 2Shanghai University of Sport, Shanghai 200438, China; 3Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China; 4the Second Affiliated Hospital of Hainan Medical University, Haikou 570100, Hainan Province, China
  • Received:2017-12-05
  • Contact: Zhu Yi, Associate professor, Associate chief technician, the Second Affiliated Hospital of Hainan Medical University, Haikou 570100, Hainan Province, China
  • About author:Cheng Jie, M.D., Associate professor, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81403477; the Natural Science Foundation of Hainan Province, No. 20168291

Abstract:

BACKGROUND: Acupuncture is a common treatment for urinary retention after spinal cord injury. It has been widely used in the clinical treatment of urinary retention after spinal cord injury due to its small side effects and simple operation. However, there is a lack of evidence-based medicine.
OBJECTIVE: To examine the effectiveness of acupuncture for urinary retention in patients with spinal cord injury by a systematic review and Meta-analysis of randomized controlled trials (RCTs).
METHODS: A computer-based online retrieval of CBM, CNKI, WanFang, Cochrane Library, PubMed, EMBASE, and Web of Science databases was performed. The keywords were “spinal cord injury, neurogenic bladder, acupuncture” in English and Chinese, respectively. RCTs concerning acupuncture or acupuncture combined with conventional therapy were identified and a Meta-analysis was conducted on RevMan 5.3 software.
RESULTS AND CONCLUSION: Nine RCTs involving 632 participants were included. In terms of urodynamic changes, compared with the control group, acupuncture was more effective in improving the residual urine volume [mean difference (MD)=-144.26, 95% confidence interval (CI) (-252.15, -36.37), P=0.009] and maximum cystometric capacity [MD=35.69, 95%CI (3.15, 68.22), P=0.03]. However, there were no significant differences between two groups for average daily number of urination [MD=-1.66, 95%CI (-3.40, 0.07), P=0.06]. Concerning total effective rate, acupuncture was more effective than control group [RR=1.24, 95%CI (1.11, 1.37), P < 0.0001]. To conclude, compared with the conventional therapy, acupuncture is more effective in improving residual urine volume, maximum cystometric capacity and total effective rate for urinary retention in patients with spinal cord injury.

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Spinal Cord Injury, Evidence-Based Medicine, Tissue Engineering

CLC Number: