Abstract: BACKGROUND: The combination of three-dimensional (3D) printing and medical workers in outpatient and digital medical education is constantly improving and developing. The application of 3D printing medical-industrial outpatient mode to the clinical practice and teaching of digital medicine will be an innovative combination during the rapid development of 3D printing. This new mode will also further promote the development of applied medicine.
OBJECTIVE: To compare the advantages of 3D printing integrated medicine-industry outpatient clinic with traditional medical teaching and 3D printing medical teaching, and expounds in detail the clinical practice teaching case of 3D printing medical worker combination clinic of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.
METHODS: The teaching methods of traditional medicine and 3D printing medicine were investigated and compared with 3D printing integrated medicine-industry outpatient clinic at Shanghai Ninth People’s Hospital affiliated to Shanghai Jiao Tong University in terms of “teaching, education, digital medicine”. We discussed the composition of 3D printing integrated medicine-industry outpatient clinic, investigated the development of 3D printing items, and summarized the number of participants who had participated in the training of 3D printing integrated medicine-industry outpatient clinic as well as the number of international conferences held in the 3D printing clinic center of Shanghai Ninth People’s Hospital from January 2018 to January 2021, thereby expounding the important role of 3D printing integrated medicine-industry outpatient clinic in the development of digital medical education.  
RESULTS AND CONCLUSION: The traditional medical education that proceeds in a large classroom is boring, in which students are easy to lose their attention and difficult to master knowledge comprehensively. 3D printing medical education could improve the understanding of abstract content in medical education, but there is a lack of clinical translation potential in 3D printing. 3D printing medical-industrial outpatient clinics could cultivate the transformation thinking of medical-industrial talents, train the students’ ability to transform scientific research achievements, and help the smooth implementation of clinical research achievements.  3D printing medical-industrial outpatient clinics at Shanghai Ninth People’s Hospital has successfully produced personalized orthoses for patients, with the characteristics of interdisciplinary interaction, medical and industrial talent interaction, and system training. It took the lead in the development and exploration of 3D printing medical-industrial outpatient clinic in the clinical practice and teaching of digital medicine, and has achieved good results. At present, there are 42 Master/MD candidates and 137 trainees in the 3D printing medical-industrial outpatient clinic. It has held 10 international conferences on rehabilitation medicine and engineering, and 6 international conferences on the clinical transformation of advanced technologies in rehabilitation medicine and engineering, all of which have a profound impact on the development of 3D printing digital medicine education over the world. To conclude, the teaching mode based on 3D printing medical-industrial outpatient clinics is not only beneficial to training students’ scientific research and innovation ability guided by clinical needs, but also conducive to the development of cutting-edge disciplines such as translational medicine, tissue engineering, rehabilitation engineering and biomedical engineering.

Key words: 3D printing outpatient, medical-industrial combination, tissue engineering, digital medical education, teaching mode, clinical teaching, scientific research innovation, achievement transformation