Chinese Journal of Tissue Engineering Research ›› 2022, Vol. 26 ›› Issue (9): 1318-1322.doi: 10.12307/2022.421

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Biomechanical analysis of non-uniform material femur under different loads

Wei Guoqiang1, Li Yunfeng1, Wang Yi1, Niu Xiaofen1, Che Lifang1, Wang Haiyan2, Li Zhijun2, Shi Guopeng1, Bai Ling1, Mo Kai1, Zhang Chenchen1, Xu Yangyang1, Li Xiaohe2, 3    

  1. 1Department of Rehabilitation Medicine, Changzhi City People’s Hospital, Changzhi 046000, Shanxi Province, China; 2Department of Anatomy, School of Basic Medicine, 3Center for Digital Medicine, Inner Mongolia Medical University, Hohhot 010110, Inner Mongolia Autonomous Region, China
  • Received:2021-05-12 Revised:2021-05-14 Accepted:2021-06-24 Online:2022-03-28 Published:2021-12-09
  • Contact: Xu Yangyang, Rehabilitation therapist, Department of Rehabilitation Medicine, Changzhi City People’s Hospital, Changzhi 046000, Shanxi Province, China Li Xiaohe, Professor, Department of Anatomy, School of Basic Medicine, and Center for Digital Medicine, Inner Mongolia Medical University, Hohhot 010110, Inner Mongolia Autonomous Region, China
  • About author:Wei Guoqiang, Master, Associate chief physician, Department of Rehabilitation Medicine, Changzhi City People’s Hospital, Changzhi 046000, Shanxi Province, China Li Yunfeng, Nurse-in-charge, Department of Rehabilitation Medicine, Changzhi City People’s Hospital, Changzhi 046000, Shanxi Province, China Wei Guoqiang and Li Yunfeng contributed equally to this article.
  • Supported by:
    National Natural Science Foundation of China, No. 81460330 (to LXH); National Natural Science Foundation of China, No. 81560348, 81860383, 81260269 (to LZJ); Science and Technology Planning Project of Inner Mongolia Autonomous Region, No. 2019 (to LXH); Young Talents in Science and Technology Project of Inner Mongolia Education Department, No. njyt-15-b05 (to LXH); Science and Technology Planning Project of Inner Mongolia Autonomous Region, No. 2016 (to LXH); Science and Technology Planning Project of Inner Mongolia Autonomous Region, No. 2019GG115 (to LZJ); Science and Technology Innovation Guidance Project of Inner Mongolia Autonomous Region, No. 2017 (to LXH); Natural Science Foundation of Inner Mongolia Autonomous Region, No. 2016MS08131, 2020MS08124, 2020LH08021 (to LXH); Returned Overseas Scholars Fund of Inner Mongolia Human Resources and Social Security Department (to LXH); Science and Technology Millions Fund Project of Inner Mongolia Medical University, No. YKD2017KJBW012 (to WHY); Follow-Up Research Project of Inner Mongolia Medical University, No. 2020 (to LXH); Science and Technology Transformation Project of Inner Mongolia Medical University, No. YKD2020CGZH009 (to LXH); Young Innovative Talents of the “Prairie Talents” Project in Inner Mongolia Autonomous Region (to LXH); “Study” Talent Category II of Inner Mongolia Medical University, No. 2021 (to LXH) 

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Abstract: BACKGROUND: The current femoral finite element model analyzes only the biomechanical studies at a single load, and the stress strain distribution of the bones under different load conditions helps to evaluate and predict the disease recovery and improve the surgical results.  
OBJECTIVE: Through the establishment of a three-dimensional model of the femur, to explore the mechanical behavior of the proximal femur in different postures of the human body, and clarify the risk area of femur fracture.
METHODS:  Based on the CT image data of the human femur, Mimics, Geomagic Studio, Hypermesh and Abaqus and other three-dimensional reconstruction softwares were used to establish a finite element model of the femur. Along the direction of gravity, on the coronal and sagittal planes of the femur, the shape surfaces were angled at -20°, -10°, 0°, +10°, +20°, a total of five groups of working conditions, and the femoral head exerted a force of 300 N. The lower part of the femur added a fixed constraint. At different positions of the femur, the distribution characteristics of stress and strain were observed under angular physiological load.  
RESULTS AND CONCLUSION: The stress and strain of the femur peaked at +10° in the coronal plane and -20° in the sagittal plane. The overall distribution of femoral stress values was femoral shaft > subtrochanteric > femoral neck; the overall distribution of femoral strain values was femoral shaft > femoral neck > subtrochanteric. The stress value and strain value of the femur could increase under the standing position of 10° hip adduction and 20° of hip abduction, and the load on the overall mechanics of the femur could increase.

Key words: femur, three-dimensional reconstruction, finite element analysis, stress, strain

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