Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (28): 4567-4572.doi: 10.12307/2021.074
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Du Yuan1, 2, Jiang Hongwei1, Li Chunqing1, Xie Yan2
Received:
2020-06-09
Revised:
2020-06-13
Accepted:
2020-08-04
Online:
2021-10-08
Published:
2021-05-22
Contact:
Xie Yan, Professor, Chief physician, Department of Geriatrics, First Affiliated Hospital of Suzhou University, Suzhou 215006, Jiangsu Province, China
About author:
Du Yuan, Associate chief physician, Department of Nephrology, Affiliated Hospital of Jiangnan University, Wuxi 214041, Jiangsu Province, China; Department of Geriatrics, First Affiliated Hospital of Suzhou University, Suzhou 215006, Jiangsu Province, China
CLC Number:
Du Yuan, Jiang Hongwei, Li Chunqing, Xie Yan. Effects of different peritoneal dialysis catheterization techniques on the prognosis of patients: a meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2021, 25(28): 4567-4572.
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2.3.1 各组腹膜透析导管感染并发症发生率差异 有10篇文献比较了经皮组和手术组腹膜透析导管相关感染并发症的发生率[3,8,11-18]。共纳入1 917例患者,经皮组1 059例,手术组858例。各研究间异质性差异有显著性意义(I2=77%,P < 0.000 1),故采用随机效应模型进行Meta分析。结果显示:在腹膜透析导管相关感染并发症的发生率方面,经皮组略低于手术组,但组间无显著性差异(OR=0.57,95%CI:0.31-1.04,P=0.07);根据研究类型的不同,将纳入的文献分成前瞻性研究亚组和回顾性研究亚组(下同)进行亚组分析,结果表明:异质性较前明显下降(I2=0%,P=0.93),亚组内比较,经皮组感染率均与手术组相似(OR=0.62,95%CI:0.09-4.37,P=0.63;OR=0.57,95%CI:0.30-1.08,P=0.08),差异无显著性意义,见图3。"
2.3.3 各组腹膜透析导管1年生存率差异 有9篇文献比较了经皮组和手术组腹膜透析导管1年生存率的情况[3,8,11-12,15-16,18-20]。共纳入1 460例患者,经皮组731例,手术组729例。各研究间异质性有显著性差异(P=0.004,I2=64%),故采用随机效应模型进行Meta分析。结果显示:在导管1年生存率方面,经皮组略高于手术组,但无显著性差异(OR=1.05,95%CI:0.68-1.64,P=0.81);亚组分析显示:异质性较前有明显下降(P=0.18,I2=44.1%),亚组内,经皮组和手术组的导管1年生存率相似(OR=0.52,95%CI:0.18-1.48,P=0.22;OR=1.13,95%CI:0.71-1.80,P=0.6),组间差异均无显著性意义,见图5。"
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