中国组织工程研究

中国组织工程研究 ›› 2015, Vol. 19 ›› Issue (37): 5938-5942.doi: 10.3969/j.issn.2095-4344.2015.37.007

• 骨组织构建 bone tissue construction • 上一篇    下一篇

低能量性髋部骨折与膝关节退变的关系

赵文杰，张  斌，高  松，周  松，王  强，戴  闽   

  1. 南昌大学第一附属医院骨科，江西省南昌市  330006
  • 出版日期:2015-09-10 发布日期:2015-09-10
  • 作者简介:赵文杰，男，1988年生，江西省南昌市人，汉族，2015年南昌大学毕业，硕士，医师，主要从事人工关节基础研究与应用。
  • 基金资助:

    江西省科技厅工程技术研究中心建设计划(20132BCD40026)

Correlation between low-energy hip fracture and knee osteoarthritis

Zhao Wen-jie, Zhang Bin, Gao Song, Zhou Song, Wang Qiang, Dai Min   

  1. Department of Orthopedics, First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
  • Online:2015-09-10 Published:2015-09-10
  • About author:Zhao Wen-jie, Master, Physician, Department of Orthopedics, First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
  • Supported by:

    the Building Plan of Engineering Technology Center of Jiangxi Provincial Department of Science and Technology, No. 20132BCD40026

PDF

352

被引次数

5

摘要：

背景：现有资料显示，膝关节是否为髋部骨折的危险因素之一，存在明显分歧。
目的：观察膝关节退变在低能量性髋部骨折中的作用及其机制。
方法：回顾性研究2014年10月至2015年1月因轻微外伤性股骨颈骨折、股骨转子间骨折而入院治疗的患者116例，男38例，女78例；发病年龄(69.2±14.5)岁；均为单纯髋关节骨折。所有患者常规拍摄双髋关节、双膝关节正侧位片。统计所有患者的临床资料，并对双侧膝关节采用Kellgren和Lawrence评分标准进行分级，行双侧膝关节HSS评分，髋关节WOMAC评分。
结果与结论：116例骨折类型为：股骨颈骨折66例，股骨转子间骨折48例，股骨转子下骨折2例；膝关节KL分级：0级0例；Ⅰ级21例；Ⅱ级51例；Ⅲ级44例；Ⅳ级0例；KL分级骨折侧平均为(2.19±0.72)级，健侧为(1.51±0.52)级，两侧差异有显著性意义(P < 0.05)；膝关节HSS评分：骨折侧为(78.4±8.09)分，健侧为(80.2±8.1)分，两侧差异有显著性意义(P < 0.05)。结果提示，膝关节退变对低暴力损伤性股骨颈骨折、股骨转子间等髋部骨折的发生具有一定作用，膝关节退行性改变可以促进股骨颈骨折、股骨转子间骨折的发生。

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

关键词: 组织构建, 骨组织工程, 膝关节退变, 股骨颈骨折, 股骨转子间骨折, HSS评分, WOMAC评分, 组织工程

Abstract:

BACKGROUND: Whether the knee is a risk factor for hip fracture is controversial.

OBJECTIVE: To investigate the effect and mechanism of knee osteoarthritis in the development of low-energy hip fracture.

METHODS: Totally 116 patients with mild traumatic femoral neck fractures and intertrochanteric fractures admitted from October 2014 to January 2015 were enrolled and retrospectively analyzed. There were 38 males and 78 females. The mean age of onset was (69.2±14.5) years, and all the patients were diagnosed as have simple hip fractures. Anterioposterior and lateral X-ray examination for the hip and knee was performed for each patient. General information, Kellgren-Lawrence grading, scores on Hospital for Special Surgery (HSS), and Western Ontario and McMaster Universities Index of Osteoarthritis were recorded and analyzed.

RESULTS AND CONCLUSION: Among the 116 cases, there were 66 cases of femoral neck fractures, 48 of intertrochanteric fractures and 2 of subtrochanteric femoral fractures. According to the Kellgren-Lawrence grading, there were 0 case of grade 0, 21 of grade I, 51 of grade II, 44 of grade III, and 0 of grade IV. Average Kellgren-Lawrence grading was 2.19±0.72 in fractured side and 1.51±0.52 in non-fractured side, and there was a significant difference between the fractured side and non-fractured side (P < 0.05). Average score of HSS was 78.4±8.09 in fractured side and 80.2±8.1 in non-fractured side, with statistical difference (P < 0.05). These findings indicate that knee osteoarthritis may have some adverse effects in the development of low-energy hip fracture, which can increase the incidence of femoral neck fracture and intertrochanteric fracture.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Knee Joint, Femoral Neck Fractures, Hip

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