中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (16): 3029-3032.doi: 10.3969/j.issn.1673-8225.2012.16.040

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

化学合成可吸收聚对二氧环己酮Ⅱ缝合线在全筋膜层连续缝合腹壁切口的应用：随机对照★

李  丹，牛跃平，王沈萍，韩广森，任潇毅，赵玉洲   

  1. 郑州大学第二附属医院普外科，河南省郑州市  450014
  • 收稿日期:2011-11-17 修回日期:2012-02-27 出版日期:2012-04-15 发布日期:2012-04-15
  • 通讯作者: 牛跃平，硕士生导师，教授，郑州大学附属第二医院普外科，河南省郑州市 450014
  • 作者简介:李丹★，男，河南省郑州市人，汉族，郑州大学在读硕士，主治医师，主要从事胃肠道肿瘤的基础与临床研究。danfer_lee@126.com

Effect of absorbable ploydioxanone II suture on full fascia continuous suture for closing an abdominal incision: Randomized controlled study

Li Dan, Niu Yue-ping, Wang Shen-ping, Han Guang-sen, Ren Xiao-yi, Zhao Yu-zhou   

  1. Department of General Surgery, Second Affiliated Hospital of Zhengzhou University, Zhengzhou  450014, Henan Province, China
  • Received:2011-11-17 Revised:2012-02-27 Online:2012-04-15 Published:2012-04-15
  • Contact: Niu Yue-ping, Master’s supervisor, Professor, Department of General Surgery, Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China
  • About author:Li Dan★, Studying for master’s degree, Attending physician, Department of General Surgery, Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China danfer_lee@126.com

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摘要：

背景：腹部切口的愈合除患者自身情况、腹部切口缝合方式外，还与缝线选择有着密切相关。
目的：观察化学合成可吸收聚对二氧环己酮Ⅱ缝合线缝合腹部切口的愈合效果。
方法：将2009-09/2011-05郑州大学第二附属医院普外科162例直肠癌患者，随机分为观察组和对照组，腹部正中切口分别采用聚对二氧环己酮Ⅱ缝合线全筋膜层连续缝合和传统丝线分层间断缝合，比较两组患者的切口愈合情况。
结果与结论：观察组切口缝合时间为(13.45±1.46) min，术后切口感染4例，无切口裂开和排异反应，经换药很快痊愈。对照组切口缝合时间为(22.96±1.95) min，术后切口感染14例，切口裂开9例，排异反应11例，经换药后部分切口延期愈合。以上数据经统计学分析，差异有显著性意义(P < 0.05)。而两组住院天数，住院费用和切口脂肪液化例数差异无显著性意义(P > 0.05)。结果可见化学合成可吸收聚对二氧环己酮Ⅱ缝合线缝合腹壁切口操作时间短，切口感染率低，并发症少，并且具有更佳的临床效果和安全性。
关键词：聚对二氧环己酮Ⅱ；缝合线；腹部正中切口；全筋膜连续缝合；直肠癌；切口愈合
缩略语注释：PDS Ⅱ：polydioxanone Ⅱ，聚对二氧环己酮Ⅱ
doi:10.3969/j.issn.1673-8225.2012.16.040

关键词: 聚对二氧环己酮Ⅱ, 缝合线, 腹部正中切口, 全筋膜连续缝合, 直肠癌, 切口愈合

Abstract:

BACKGROUND: The healing of abdominal incisions is closely related to the choice of suture, besides patients’ health and the suturing ways to close an abdominal incision.
OBJECTIVE: To investigate the effect of absorbable ploydioxanone II suture (PDS Ⅱ) at the healing of abdominal incisions.
METHODS: Totally 162 patients with rectal cancer were collected from the Second Affiliated Hospital of Zhengzhou University from September 2009 to February 2011, and they were randomly divided into observation group and control group. Patients in the observation group were performed full fascia continuous suture by using PDS Ⅱ, while patients in the control group were performed layering intermittent silk suture. Wound healing in the two groups was compared.
RESULTS AND CONCLUSION: In the observation group, the mean suture time was (13.45 ± 1.46) minutes, and four cases were found wound infection postoperatively, but they were soon healed by dressing with no wound dehiscence and rejection reaction. The mean suture time of the control group was (22.96±1.95) minutes, and 14 cases were found wound infection, among which, wound dehiscence appeared in nine cases and rejection reaction appeared in 11 cases. In the control group, some patients had delayed healing by dressing. There were significant differences between the two groups (P < 0.05). In terms of hospital days, expenses and cases of fat liquefaction, there was no significant difference between the two groups (P > 0.05). These findings suggest that PDS Ⅱ for abdominal incision suture has a shorter operation time, lower rate of incision infection, fewer complications, as well as better clinical effect and security. 

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