中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (8): 1507-1510.doi: 10.3969/j.issn.1673-8225.2011.08.043

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

流动纳米树脂预防性窝沟龋充填

谢富强,颉伟博,刘国华,孙  健,胡朝昶   

  1. 兰州大学第二医院口腔科,甘肃省兰州市   730030
  • 收稿日期:2010-09-13 修回日期:2010-11-11 出版日期:2011-02-19 发布日期:2011-02-19
  • 作者简介:谢富强,男,1965年生,甘肃省甘谷县人,汉族,1990年华西医科大学毕业,教授,主要从事生物材料的研究。 xiefq@lzu.edu.cn
  • 基金资助:

    兰州市科技发展计划项目基金资助课题(07-1-99)。

Flowable nano-resin in preventive pit and fissure caries restoration

Xie Fu-qiang, Xie Wei-bo, Liu Guo-hua, Sun Jian, Hu Chao-chang   

  1. Department of Stomatology, the Second Hospital Affiliated to Lanzhou University, Lanzhou   730030, Gansu Province, China
  • Received:2010-09-13 Revised:2010-11-11 Online:2011-02-19 Published:2011-02-19
  • About author:Xie Fu-qiang, Professor, Department of Stomatology, the Second Hospital Affiliated to Lanzhou University, Lanzhou 730030, Gansu Province, China xiefq@lzu.edu.cn
  • Supported by:

     the Science and Technology Development of Lanzhou, No. 07-1-99*

摘要:

背景:预防性树脂充填术由于不采用传统的预防性扩展,只去除少量的龋坏组织后即用复合树脂或玻璃离子材料充填龋洞,而未患龋的窝沟使用封闭剂保护。
目的:通过应用美国3M公司生产的Filtek Z350流动纳米树脂对窝沟可疑龋、初龋磨除后进行预防性充填,观察并评价其临床效果,探索预防性充填治疗早期窝沟龋的新方法。
方法:对196例6~25岁患者磨牙的牙合 面窝沟龋在去除龋坏的牙体组织后,采用Eadper prompt自酸蚀粘结技术,用Filtek Z350流动纳米树脂对整个牙面进行预防性充填术,并采用对侧同名牙或邻牙也有窝沟龋者用同一公司生产的ClinproTM可见光固化变色窝沟封闭剂充填作对照研究。
结果与结论:随治4年后发现该方法涂膜保留率高,能有效阻止龋病的进一步发展。实验组与对照组在术后1,2年时的涂膜保留率差异无显著性意义,而在第3,4年时差异有显著性意义(P < 0.01、P < 0.05)。龋病发生率在1,2年时差异无显著性意义,而在3,4年时差异有显著性意义(P < 0.05)。提示Filtek Z350流动纳米树脂预防性窝沟充填是一种有效阻止窝沟早期龋进一步发展的方法。

关键词: 窝沟龋, Filtek Z350流动纳米树脂, 治疗效果, 预防性充填, 口腔生物材料

Abstract:

BACKGROUND: Without use of traditional precautionary expansion, preventive resin restorations only remove a small amount of decayed tissue and immediately fill caries with composite resin or glass ionomer materials, while the pit and fissure without caries are prevented using a sealant.
OBJECTIVE: To evaluate the clinical effect of Filtek Z350 flowable nano-composite resin (3M, USA) in molar occlusal pit and fissure caries, and to explore a new preventive restoration for pit and fissure caries.
METHODS: A total of 350 permanent molars with occlusal pit and fissure caries in 196 patients aged from 6 to 25 years were treated with Filtek Z350 flowable nano-composite resin after the cariated tissue had been removed. The opposite or adjacent teeth also with similar caries in the identical patients were treated with ClinproTM light cure pit and fissure sealant as the control.
RESULTS AND CONCLUSION: After the patients were followed up for 4 years, Filtek Z350 flowable nano-composite resin can exhibit high retention rate and effectively prevent the caries development. There were significant differences in the retention rate and caries incidence between study group and control group within 1-2 years postoperation, but significant differences could be observed within 3-4 years postoperation (P < 0.01, P  < 0.05). Filtek Z350 flowable nano-composite resin can be effectively used to treat and prevent molar pit and fissure caries.

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