中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (34): 6417-6420.doi: 10.3969/j.issn.1673-8225.2010.34.036

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

可吸收缝合线体外降解及在妇产科临床的应用

叶丽萍，程桂平，张  晋   

  1. 辽宁省人民医院妇产科，辽宁省沈阳市  110016
  • 出版日期:2010-08-20 发布日期:2010-08-20
  • 作者简介:叶丽萍，女，1966年生，辽宁省辽阳县人，1996年辽宁中医药大学毕业，副主任护师，主要从事妇产科疾病的研究与护理研究。 lipingye2003@yahoo.com.cn

In vitro degradation of absorbable sutures and their clinical application in gynecology and obstetrics

Ye Li-ping, Cheng Gui-ping, Zhang Jin   

  1. Department of Gynecology and Obstetrics, People’s Hospital of Liaoning Province, Shenyang   110016, Liaoning Province, China
  • Online:2010-08-20 Published:2010-08-20
  • About author:Ye Li-ping, Associate chief nurse, Department of Gynecology and Obstetrics, People’s Hospital of Liaoning Province, Shenyang 110016, Liaoning Province, China lipingye2003@yahoo.com.cn

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摘要：

目的：探讨可吸收缝线在妇产科中的应用。
方法：由第一作者应用计算机检索维普数据库(网址http://www.cqvip.com/)有关可吸收缝合线在妇产科手术护理中应用的文献，检索词为“可吸收缝合线；妇产科；护理；生物材料”，排除重复性研究。计算机初检得到54篇文献，根据纳入标准保留18篇进一步归纳总结。
结果：随着医学模式的转变和人们对生活质量要求的不断提高，可吸收缝线作为一种生物材料，由于其良好的生物相容性及机械强度，在外科手术中应用得越来越为广泛。尤其对妇产科手术患者有非常重要的临床意义和远期效果。此类缝线可以在外科手术时间的缩短、术后感染率的降低、术后机体的恢复及减少切口内异物的刺激、疼痛的减轻等方面对患者个人、科室及医院的管理都体现出了重大的意义。因而在对妇产科手术缝合方面有非常重要的指导作用。此外，针对其降解产物所进行的有效分析，临床工作者应注重对各种缝线进行横向比较，对其在生物体内的降解安全性尚需结合进一步的体内降解试验及毒性动力学的研究来进行综合推断，以保障其临床效果更为完善地发挥。
结论：可吸收缝线作为一种生物材料，由于其良好的生物相溶性及机械强度，在外科手术中应用得越来越为广泛。妇产科诸如剖宫产手术、会阴侧切及会阴撕裂伤的缝合中，临床医生及患者应倾向于选用可吸收缝线来进行手术切口和伤口的有效缝合。

关键词: 可吸收, 缝合线, 妇产科, 护理, 生物材料

Abstract:

OBJECTIVE: To investigate the application of absorbable sutures in obstetrics and gynecology.
METHODS: A computer search was performed by the first author in VIP database (http://www.cqvip.com/) for articles abiout the absorbable sutures applied in surgical nursing of obstetrics and gynecology, using the key words “absorbable sutures; obstetrics and gynecology; care; biological materials”. Repeated researches were excluded. Totally 54 literatures were primarily screened out, according to inclusion criteria, 18 of them were involved in further summary.
RESULTS: With the transformation of medical model and increasing requirement of people for quality of life, absorbable suture as a kind of biomaterials, has been widely applied in surgery due to its excellent biocompatibility and mechanical strength, particularly have a very important clinical significance and long-term results for obstetric and gynecological surgery patients. Such sutures can reduce surgical time and postoperative infection rates, promote postoperative recovery and decrease the foreign body to wound, relieve pain for individual patients, also have reflected a significance on departments and hospital management. Suture plays a very important guide role for obstetric and gynecological surgery. In addition, effective analysis for its degradation products shows that, clinicians should focus on horizontal comparison among a variety of sutures, its degradation security in vivo still need to concluded integrating with in vivo degradation test and toxicity kinetics studies, so as to ensure its clinical effect.
CONCLUSION: The absorbable sutures as a biomaterial have achieved an increasingly application in surgery due to its good biological compatibility and mechanical strength. As for obstetrics and gynecology, such as cesarean section, episiotomy and perineal tears sutures, the clinicians and patients tend to use absorbable suture for surgical suture and effective suture of the wound.

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