中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (16): 2941-2944.doi: 10.3969/j.issn.1673-8225.2010.16.023

• 生物材料综述 biomaterial review • 上一篇    下一篇

前交叉韧带重建与移植物的选择

郝建学1，高石军2，刘锁利1，万建设1   

  1. 1保定市第一医院骨科，河北省保定市  071000；2河北省医科大学第三医院关节骨科，河北省石家庄市  050051
  • 出版日期:2010-04-16 发布日期:2010-04-16
  • 通讯作者: 高石军，硕士，教授，河北省医科大学第三医院关节骨科，河北省石家庄市 050051 gaoshijun@126.com
  • 作者简介:郝建学★，男，1976年生，河北省清苑县人，汉族，2008年河北医科大学毕业，硕士，主治医师，主要从事关节外科，创伤外科研究。 hjx1976sxy@yahoo.com.cn

Reconstruction of anterior cruciate ligament and graft selection

Hao Jian-xue1, Gao Shi-jun2, Liu Suo-li1, Wan Jian-she1   

  1. 1 Department of Orthopaedics, Baoding First Hospital, Baoding   071000, Hebei Province, China; 2 Department of Joint Orthopaedics, Third Hospital of Hebei Medical University, Shijiazhuang   050051, Hebei Province, China
  • Online:2010-04-16 Published:2010-04-16
  • Contact: Gao Shi-jun, Master, Professor, Department of Joint Orthopaedics, Third Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei Province, China gaoshijun@126.com
  • About author:Hao Jian-xue★, Master, Attending physician, Department of Orthopaedics, Baoding First Hospital, Baoding 071000, Hebei Province, China hjx1976sxy@yahoo.com.cn

PDF

477

被引次数

15

摘要：

背景：前交叉韧带重建移植物的选择以及重建后移植物的组织学转归一直是前交叉韧带修复与重建领域的一个重要的研究课题。
目的：就前交叉韧带的结构，移植物的选择问题进行综述。
方法：以Anterior cruciate ligament、implant、reconstruction为检索词，检索Medline数据库1980-01/2010-01相关文献。纳入标准：①前交叉韧带损伤重建手术相关文献。②前交叉韧带移植物选择相关文献。排除标准：①较陈旧的文献。②重复研究。共收集250篇关于关节镜下前交叉韧带重建的文献，排除发表时间较早、重复及类似研究，纳入33篇符合标准的文献。
结果与结论：目前，前交叉韧带断裂主要治疗方法为关节镜和关节镜辅助下前交叉韧带重建术。前交叉韧带重建术临床应用的移植物很多，包括自体移植物、同种异体移植物、异种异体移植物、生物材料、人工材料和组织工程学移植物。应用自体半腱肌腱和股薄肌腱或者应用自体骨-髌腱(中1/3)-骨(BPTB)重建前交叉韧带的方法是国内外重建前交叉韧带的主要方法。

关键词: 前交叉韧带, 移植物, 重建, 肌肉肌腱, 生物材料, 综述文献

Abstract:

BACKGROUND: Graft selection and histological fate for anterior cruciate ligament reconstruction is a hot topic in the fields of reconstruction and repair of anterior cruciate ligament.
OBJECTIVE: To review structure of anterior cruciate ligament and graft selection.
METHODS: Articles were retrieved from Medline database with the key words of “Anterior cruciate ligament, implant, reconstruction” between January 1980 and January 2010. Inclusion criteria: ① Reconstructive surgery of anterior cruciate ligament injury; ② graft selection of anterior cruciate ligament. Exclusion criteria: ① the old literatures; ② repetitive studies. A total of articles related to reconstruction of anterior cruciate ligament were retrieved, but 33 ones were included in the final analysis. The old, duplicated, and similar studies were excluded.
RESULTS AND CONCLUSION: At present, the major therapy for anterior cruciate ligament injury includes arthroscopy and arthroscopy-assisted reconstruction. For clinical application, there are a lot of grafts, including autogenous grafts, allografts, heterologous allograft, biological materials, artificial materials and tissue engineering grafts. Autogenous semitendinosus tendon and gracilis tendon or autogenous bone - patellar tendon (middle 1/3) - bone (BPTB) are mainly used for anterior cruciate ligament reconstruction at home and abroad.

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