中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (8): 1475-1478.doi: 10.3969/j.issn.1673-8225.2010.08.035

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

后房型人工晶体植入有晶体眼矫正高度近视的安全性与稳定性：11例随访

邹莺英，毕宏生，解孝锋   

  1. 山东中医药大学眼科中心，山东施尔明眼科医院，山东省济南市  250014
  • 出版日期:2010-02-19 发布日期:2010-02-19
  • 通讯作者: 毕宏生，教授，主任医师，山东中医药大学眼科中心，山东施尔明眼科医院，山东省济南市 250014 b66hong66@yahoo.com.cn
  • 作者简介:邹莺英★，女，1982年生，山东省莱州市人，汉族，山东中医药大学在读硕士，主要从事眼科疾病治疗方面的研究。 zou501@163.com

Safety and stability of posterior chamber phakic intraocular lens for correction of extreme myopia: A follow-up of 11 cases

Zou Ying-ying, Bi Hong-sheng, Xie Xiao-feng   

  1. Eye Center of Shandong University of Traditional Chinese Medicine, Shierming Eye Hospital, Jinan  250001, Shandong Province, China
  • Online:2010-02-19 Published:2010-02-19
  • Contact: Bi Hong-sheng, Professor, Chief physician, Eye Center of Shandong University of Traditional Chinese Medicine, Shierming Eye Hospital, Jinan 250001, Shandong Province, China b66hong66@yahoo.com.cn
  • About author:Zou Ying-ying★, Studying for master’s degree, Eye Center of Shandong University of Traditional Chinese Medicine, Shierming Eye Hospital, Jinan 250001, Shandong Province, China zou501@163.com

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摘要：

背景：有晶体眼人工晶体植入术具有潜在的可逆性和保留了调节力等优点，是目前富有潜力的屈光手术。而后房型有晶体眼人工晶体植入术是近几年发展起来的矫正高度近视的方法，有其独特的优越性。
目的：探讨有晶体眼后房型人工晶体植入术矫正高度近视的稳定性、有效性和安全性。
方法：选择2006-03/2009-01在山东施尔明眼科医院行后房型有晶体眼人工晶体植入矫正高度近视患者11例(18眼)，男4例(7眼)，女7例(11眼)。术后随访3~6个月(平均5.3个月)，观察屈光度、眼压、对比敏感度、眩光敏感度、角膜内皮计数及晶体的混浊情况等。
结果与结论：术后6个月裸眼视力均≥术前矫正视力，术后散光明显减轻，裸眼对比敏感度及眩光敏感度值在全频明显提高，术后6个月前房深度、角膜内皮细胞数及眼压与术前比较无明显变化；随访6个月未出现严重并发症；2例患者出现夜间视力降低及眩光的现象。说明短期内观察有晶体眼后房型人工晶体植入矫正高度近视具有良好的可预测性、安全性和稳定性，是一种颇具前途的高度近视矫治方法。

关键词: 有晶状体眼, 人工晶状体, 高度近视, 后房, 生物材料

Abstract:

BACKGROUND: The phakic intraocular lens implantation has advantages of reversibility and accommodative capability, which is a promising refractive operation. Posterior chamber phakic intraocular lens implantation is a developing method for the correction of extreme myopia. 
OBJECTIVE: To evaluate the efficacy, safety and stability of posterior chamber phakic intraocular lens implantation for the correction of extreme myopia. 
METHODS: This study included 18 eyes of 11 patients whose received posterior chamber phakic intraocular lens implantation at Shierming Eye Hospital from March 2006 to January 2009, including 4 males (7 eyes) and 7 females (11 eyes). All patients were followed-up 3-6 months, mean 5.3 months. The refraction, intraocular pressure, contrast sensitivity, glare sensitivity, endothelial cell morphometry, as well as lens opacities were observed. 
RESULTS AND CONCLUSION: After operation, naked visions of the 18 eyes were better than or equal to preoperative corrective vision, and the astigmatism was relieved obviously. The naked contrast sensitivity and glare sensitivity was better than that before the operation. The anterior chamber depth, intraocular pressure and corneal endothelium counting before and after the operation had no significant difference. No serious complication was detected during the follow-up. The vision decent at night and dazzling sensation occurred in 2 cases. Shot-term observation shows that implanting intraocular lens in posterior chamber to correct high myopia is safe, stable and predictable. This operation is a promising method for correcting high myopia. 

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