Chinese Journal of Tissue Engineering Research ›› 2018, Vol. 22 ›› Issue (7): 1026-1031.doi: 10.3969/j.issn.2095-4344.0112

Previous Articles     Next Articles

Related factors for dysphagia after single-level anterior cervical descectomy and fusion

Lu Ying-jie, Bao Wei-guo, Zou Jun, Zhou Feng, Jiang Wei-min, Yang Hui-lin, Zhang Zhi-ming, Zhu Xue-song   

  1. Department of Orthopedics, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
  • Online:2018-03-08 Published:2018-03-08
  • Contact: Zhang Zhi-ming, M.D., Associate chief physician, Department of Orthopedics, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China Zhu Xue-song, M.D., Researcher, Department of Orthopedics, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
  • About author:Lu Ying-jie, Studying for master’s degree, Department of Orthopedics, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81772358; the National High Technology Research and Development Program of China (863 Program), No. 2015AA020316

Abstract:

BACKGROUND: Patients with anterior cervical discectomy and fusion have a high incidence of dysphagia, which may be associated with a variety of factors. The specific mechanism remains unclear.

OBJECTIVE: To explore the related factors of dysphagia after single-level anterior cervical discectomy and fusion.
METHODS: We retrospectively analyzed patients with cervical degenerative disc disease receiving single-level anterior cervical discectomy and fusion in First Affiliated Hospital of Soochow University from January 2011 to January 2015. During hospitalization, basic patient data and surgery-related data were recorded, including operation time, intraoperative blood loss, surgical segment, internal fixation device and the use of recombinant human bone morphogenetic protein-2. The cervical alignment and prevertebral soft tissue swelling were measured preoperatively and 3 days postoperatively. At 1, 3, 6, 12, and 24 months postoperatively, the Bazaz swallowing function scoring system was used to assess the swallowing of the patients.
RESULTS AND CONCLUSION: A total of 262 patients undergoing single-level anterior cervical discectomy and fusion were involved. The incidence of dysphagia at 1, 3, 6, 12, and 24 months postoperatively was 35.9%, 22.9%, 15.6%, 11.5% and 9.2% respectively. Univariate analysis showed that gender, operation time and course length were associated with postoperative dysphagia. Logistic multivariate regression analysis showed that the duration of operation (≥ 3 hours), female and course length (≥ 8 months) were risk factors for dysphagia after anterior cervical descectomy and fusion. Operation time and female may be associated with early and middle dysphagia postoperatively, and the course length may be associated with chronic dysphagia. Prevertebral soft tissue swelling and other factors are not related to dysphagia after single-level anterior cervical discectomy and fusion. Risk factors for dysphagia after multi-level fusion should be further studied.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Cervical Vertebrae, Spinal Fusion, Postoperative Complications, Dysphagia, Tissue Engineering

CLC Number: