中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (30): 5650-5653.doi: 10.3969/j.issn.1673-8225.2010.30.034

• 骨与关节学术探讨 academic discussion of the bone and joint • 上一篇    下一篇

人工膝关节置换后的假体周围感染

方  恺   

  1. 上海市第九人民医院骨科，上海市  200011
  • 出版日期:2010-07-23 发布日期:2010-07-23
  • 作者简介:方 恺★，男，1985年生，上海市人，汉族，2010年上海交通大学医学院毕业，硕士，主要从事膝骨关节炎方面的研究。 fk571@hotmail.com

Periprosthetic infection following artificial knee replacement

Fang Kai   

  1. Department of Orthopedics, Shanghai Ninth People’s Hospital, Shanghai  200011, China
  • Online:2010-07-23 Published:2010-07-23
  • About author:Fang Kai★, Master, Department of Orthopedics, Shanghai Ninth People’s Hospital, Shanghai 200011, China fk571@hotmail.com

PDF

787

被引次数

31

摘要：

目的：总结近年有关人工膝关节置换后出现假体周围感染的现状。
方法：由作者应用计算机检索维普数据库中与人工膝关节置换后出现假体周围感染有关的文献，检索时限1998-01/2009-10。检索词：膝关节；全膝置换；感染。对资料进行初审，并查看每篇文献后的引文。共入选18篇文献进一步分析。
结果：膝关节置换后持续性疼痛和进行性关节僵直应高度怀疑深部感染。血沉、C-反应蛋白及关节穿刺物的培养是诊断感染的重要指标。单纯使用抗生素治疗不能去除深部感染，并且预后较差。使用抗生素骨水泥进行Ⅱ期翻修是去除感染的最有效治疗方案。
结论：全膝关节置换后感染是十分严重的并发症，一旦发生感染应及早进行诊断，同时根据病情选择合适的治疗方案。

关键词: 膝关节, 假体置换, 感染, 并发症, 医学植入体

Abstract:

OBJECTIVE: To summarize current state of periprosthetic infection following artificial knee replacement.
METHODS: A computer-based online search of VIP was performed for articles related to periprosthetic infection following artificial knee replacement published between January 1998 and October 2009, with the key words “knee joint, total hip replacement, infection”. The data were collected, and references of each article were reviewed. A total of 18 articles were included.
RESULTS: Continuous pain and progressive joint stiffness following knee replacement may be a result of infection. Blood sedimentation, C-reactive protein and culture of joint drainage are main indexes of infection. Antibiotics alone cannot treat deep infection, and the prognosis is not favorable. Antibiotic-loaded articulating cement is an effective therapy for injection in revision at stagy II.
CONCLUSION: Infection following total knee replacement is very severe complication. It is necessary to diagnose infection early and treat using appropriate methods based on condition of disease.

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