中国组织工程研究

• 骨与关节学术探讨 academic discussion of the bone and joint • 上一篇    下一篇

血管内支架置入在缺血性脑血管病的应用及影像学评估

严福华   

  1. 井冈山大学附属医院CT室,江西省吉安市   343000
  • 出版日期:2010-07-23 发布日期:2010-07-23
  • 作者简介:严福华,男,1972年生,江西省吉安市人,汉族,2005年华中科技大学毕业,主治医师,主要从事影像学方面的研究。ufh8852951.hi@163.com

Application and imaging evaluation of endovascular stents in ischemic cerebrovascular diseases

Yan Fu-hua   

  1. CT Room, Affiliated Hospital of Jinggangshan University, Ji’an  34300, Jiangxi Province, China
  • Online:2010-07-23 Published:2010-07-23
  • About author:Yan Fu-hua, Attending physician, CT Room, Affiliated Hospital of Jinggangshan University, Ji’an 34300, Jiangxi Province, China ufh8852951.hi@163.com

摘要:

背景:目前对于缺血性脑血管病影像检测手段广泛应用于临床,并且有无创、快速、简便等优点。
目的:观察血管内支架置入后影像形态学变化,探讨血管内支架在缺血性脑血管病中应用安全性及不同材料的应用价值。
方法:以 “血管内支架,支架材料,再狭窄,影像”为中文关键词;以:“vascular stent,scaffold,restenosis,endothelialization,imaging evaluation”为英文关键词,采用计算机检索1993-01/2009-10相关文章。纳入与不同材料支架置入后颅内靶血管再狭窄的影像形态学评估有关的文章;排除重复研究或Meta分析类文章。以30篇文献为主重点进行讨论不同材料血管内支架在缺血性脑血管病中应用安全性及影像学评价。
结果与结论:按置入支架材料不同类型的患者采用影像学技术,观察随访期间靶血管再狭窄形态学变化。可以明确有无血管狭窄、明确病因,并有利于对血管内支架材料的选择进行风险-效益评估。提示:影像判断不同材料支架置入后形态学差异有较高的敏感性、特异性和准确性,有助于选择支架材料及对术中病变部位栓子脱落危险性的评估。

关键词: 血管内支架, 支架材料, 再狭窄, 内皮化, 影像学评估

Abstract:

BACKGROUND: Imaging detection has been widely used in clinical ischemic cerebrovascular disease, which is noninvasive, simple and rapid.
OBJECTIVE: To observe imaging morphological changes following endovascular stent implantation to explore safety and values of endovascular stent in ischemic cerebrovascular disease.
METHODS: A computer-based online search was performed for related articles published from January 1993 to October 2009 with the key words “vascular stent; scaffold; restenosis; endothelialization; imaging evaluation”. Articles related to imaging morphological evaluation of intracranial target vascular restenosis following stenting of different materials. Repetitive studies or Meta analysis was excluded. A total of 30 articles were selected to discuss safety and imaging evaluation of different materials of stent for ischemic cerebrovascular disease.
RESULTS AND CONCLUSION: Intracranial target vascular restenosis following stenting of different materials was observed during follow-up by imaging to identify restenosis and confirm cause, which facilitates evaluation of risks and effect of stent materials. Imaging is sensitive, specific and accurate to identify morphological changes following different materials of stent implantation to help material selection and evalution of embolus shedding at lesioned site.

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