中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (29): 5437-5440.doi: 10.3969/j.issn.1673-8225.2011.29.029

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

左炔诺孕酮宫内缓释系统在妇科疾病治疗中的作用

李广华，何金良   

  1. 南昌市第二医院医院妇产科，江西省南昌市     330002
  • 收稿日期:2011-02-01 修回日期:2011-04-18 出版日期:2011-07-16 发布日期:2011-07-16
  • 作者简介:李广华，1977年生，江西省南昌市人，汉族，2002年江西医学院毕业，主治医师，主要从事妇科疾病治疗研究。 hxq33@126.com

Effects of levonorgestrel-releasing intrauterine system in treating gynecological diseases

Li Guang-hua, He Jin-liang   

  1. Department of Gynaecology and Obstetrics, Nanchang Second Hospital, Nanchang  330002, Jiangxi Province, China
  • Received:2011-02-01 Revised:2011-04-18 Online:2011-07-16 Published:2011-07-16
  • About author:Li Guang-hua, Attending physician, Department of Gynaecology and Obstetrics, Nanchang Second Hospital, Nanchang 330002, Jiangxi Province, China hxq33@126.com

PDF

479

被引次数

40

摘要：

背景：左炔诺孕酮宫内缓释系统有很高的避孕可靠性，可对子宫内膜产生明显的抑制作用。
目的：阐述左炔诺孕酮宫内缓释系统在妇科疾病治疗中的作用。
方法：由第一作者检索CBM、PubMed数据库(http://www.ncbi.nlm.nih.gov/PubMed)、万方数据库(http://www. wanfangdata.com.cn)及google学术网1990/2010有关左炔诺孕酮宫内缓释系统治疗妇科疾病的文献，排除重复性研究。
结果与结论：共保留17篇文献进行归纳总结。结果显示，左炔诺孕酮宫内缓释系统作为释放微量孕激素的宫内缓释系统，可安全、有效地应用于避孕，治疗月经过多、内异症、子宫腺肌病，以及激素替代治疗中对子宫内膜的保护等，对治疗子宫肌瘤引起的月经过多也有良好效果。提示左炔诺孕酮宫内缓释系统治疗妇科疾病效果显著，但还需要大样本、长期的临床研究加以验证。

关键词: 左炔诺孕酮宫内缓释系统, 妇科, 子宫出血, 子宫内膜异位症, 子宫腺肌病, 治疗

Abstract:

BACKGROUND: Levonorgestrel-releasing intrauterine system is reliable in contraception by inhibiting endometrium.
OBJECTIVE: To elucidate effects of levonorgestrel-releasing intrauterine system in treating gynecological diseases.
METHODS: A computer-based online search of CBM, PubMed database (http://www.ncbi.nlm.nih.gov/PubMed), Wanfang database (http://www.wanfangdata.com.cn), and google search was performed for articles related to levonorgestrel-releasing intrauterine system in treating gynecological diseases, published between 1990 and 2010. Repetitive studies were excluded.
RESULTS AND CONCLUSION: A total of 17 articles were included. As intrauterine progestogen-releasing system, levonorgestrel-releasing intrauterine system can be used as a safe and effective contraception method. In addition, it can treat menorrhagia, endometriosis, adenomyosis, protect endometrium, and ameliorate hysteromyoma-induced menorrhagia. Results revealed that levonorgestrel-releasing intrauterine system can effectively treat gynecological diseases. However, large-sample, long-term clinical studies are required.

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