中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (48): 9023-9026.doi: 10.3969/j.issn.1673-8225.2011.48.023

• 骨与关节图像与影像 bone and joint imaging • 上一篇    下一篇

64层CT造影断层图像虚拟技术和CT仿真结肠镜的临床应用

俞金龙1，崔春晖1，黄宗海1，黄淑馨2，邹兆伟1   

  1. 南方医科大学珠江医院，1普通外科，2眼科，广东省广州市510280
  • 收稿日期:2011-09-21 修回日期:2011-10-15 出版日期:2011-11-26 发布日期:2011-11-26
  • 通讯作者: 黄宗海，主任医师，教授，博士生导师，南方医科大学珠江医院普通外科，广东省广州市510280
  • 作者简介:俞金龙☆，男，1964年生，江西省南昌市人，汉族，2009年南方医科大学毕业，博士，副主任医师，副教授，主要从事普通外科研究。 yujingl@163.net music201@qq.com
  • 基金资助:

    广东省自然科学基金项目(101510515010 00026)。

Clinical application of virtual technology based on 64-slice CT angiography images and CT virtual colonoscopy

Yu Jin-long1, Cui Chun-hui1, Huang Zong-hai1, Huang Shu-xin2, Zou Zhao-wei1   

  1. 1Department of General Surgery, 2Department of Ophthalmonogy, Zhujiang Hospital of Southern Medical University, Guangzhou  510280, Guangdong Province, China
  • Received:2011-09-21 Revised:2011-10-15 Online:2011-11-26 Published:2011-11-26
  • Contact: Huang Zong-hai, Chief physician, Professor, Doctoral supervisor, Department of General Surgery, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China
  • About author:Yu Jin-long☆, Doctor, Associate chief physician, Associate professor, Department of General Surgery, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China yujingl@163.net, music201@qq.com
  • Supported by:

     the Natural Science Foundation of Guangdong Province, No. 10151051501000 026*

PDF

406

被引次数

6

摘要：

背景：虚拟内窥镜能够充分显示结肠的解剖形态以及病变部位，并从狭窄、梗阻处两端观察肠腔的解剖和病变。结合三维图像还可了解肠壁以及腔外的情况，更有利于肿瘤的定性以及分期诊断。
目的：探讨64层CT造影断层图像虚拟技术和64层螺旋CT三维成像与仿真内镜在结肠肿瘤诊断中的应用价值。
方法：应用Philips/Brilliance 64 CT对10例术后病理标本证实的结肠癌(8例)和结肠息肉(2例)进行容积扫描。Mimics软件用Marching Cubes算法对肠管进行面绘制及用虚拟内镜法重建三维图像及基于CT造影二维图像对大肠及周围结构等各种组织进行三维重建，并与Brilliance workspace工作站三维成像和仿真内镜结果相比较。
结果与结论：10例三维成像效果良好，虚拟内镜与CT仿真内镜显示基本一致。虚拟结肠镜结合多结构数字模型重建可以提供更多信息，有助于病变的准确定位，能准确反映其复杂的解剖结构及空间毗邻关系。说明64层CT造影断层图像虚拟技术能达到与CT仿真内镜结合三维成像同样的敏感性和特异性，加上各种组织三维重建技术可以提供较仿真内镜更丰富的信息。

关键词: 血管造影, CT 图像, 数字模型, 虚拟技术, 多层螺旋CT, 虚拟内窥镜, Mimics, 数字化图像与影像

Abstract:

BACKGROUND: Virtual endoscopy can fully display the anatomy form and pathological changes of the colon at both ends of stenosis and obstruction sites. Combined with three-dimensional (3D) images, we can also understand the conditions of the bowel wall and external cavity, which is more advantageous to the qualitative and stage diagnosis of tumors.
OBJECTIVE: To investigate the application value of virtual technology based on 64-slice CT angiography (CTA) images, 64-slice CT 3D imaging and virtual endoscopy in the diagnosis of colon tumors.
METHODS: Philips/Brilliance 64 CT volumetric scanning was performed in 10 patients with colonic diseases confirmed based on postoperative pathological specimens, including 8 cases of colon tumors and 2 of colonic polypi. Mimics software was used for the surface rendering of the intestine with the Marching Cubes algorithm followed by virtual endoscope 3D reconstruction, and 3D reconstruction of the large intestine and surrounding tissues was done using the Mimics software based on the CTA two-dimensional images. The reconstructed 3D models were compared with 3D images and virtual endoscopy results obtained in the Brilliance workspace.
RESULTS AND CONCLUSION: Satisfied results were achieved from 3D images of 10 patients, and there were no significant differences between the findings of virtual endoscopy and CT virtual endoscopy. Virtual colonoscopy combined with multi-structure digital model reconstruction could provide more information, which was helpful to accurately locate the lesion position and could precisely show complex anatomical structures and spatial adjacent relations. Virtual technologies based on 64-slice CTA images nearly have the same sensitivity and specificity as CT virtual endoscopy combined with 3D images. The former one combined with 3D reconstruction techniques in various tissues can provide  more information than CT virtual endoscopy.

中图分类号: