中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (17): 3222-3225.doi: 10.3969/j.issn.1673-8225.2010.17.046

• 骨与关节学术探讨 academic discussion of the bone and joint • 上一篇    下一篇

中医药在脑血管支架置入后防治并发症中的作用

梁  红   

  1. 沈阳医学院沈洲医院内科，辽宁省沈阳市  110002
  • 出版日期:2010-04-23 发布日期:2010-04-23
  • 作者简介:梁 红★，女，1971年生，山东省黄县人，汉族，1994年辽宁中医药大学毕业，硕士，副主任医师，主要从事中医药与介入研究。

Role of traditional Chinese medicine in prevention and treatment of complications after cerebrovascular stent placement

Liang Hong   

  1. Department of Internal Medicine, Shenzhou Hospital, Shenyang Medical College, Shenyang   110002, Liaoning Province, China
  • Online:2010-04-23 Published:2010-04-23
  • About author:Liang Hong★, Master, Associate chief physician, Department of Internal Medicine, Shenzhou Hospital, Shenyang Medical College, Shenyang 110002, Liaoning Province, China tcmqq@qq.com

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摘要：

目的：评价中医药在脑血管支架置入后并发症中的作用效果。
方法：应用计算机检索Science Direct 数据库、Ei数据库1960-01/2009-10期间的相关文章，检索词为“traditional Chinese medicine，stent placement，complication”，并限定文章语言种类为English。同时计算机检索中国期刊全文数据库、中国生物医学文献数据库等1994-01/2009-10期间的相关文章，检索词为“中医药，脑血管，支架置入，并发症”，并限定文章语言种类为中文。此外还手工查阅相关专著数部。纳入有关中医药防治脑血管支架置入后并发症的基础与临床实验。
结果：脑血管支架置入后的中医药干预方法以益气、活血、涤痰为基本治法,亦可佐以疏肝理气、安神利水、凉血止血之品。常用的中药复方有生脉散、补阳还五汤、血府逐瘀汤加减、四逆汤及抵挡汤加减等。现代药理学研究表明，大量益气活血化瘀涤痰的中药及复方，通过多组分、多靶点、多途径的整合调节作用，有效地干预脑血管支架置入后并发症的发生。
结论：对脑血管支架置入围手术期进行中医药干预，发挥中医药特色，对于提高手术成功率，防治、减少围手术期及远期并发症具有重要意义。

关键词: 脑血管, 支架置入, 中医药, 医学植入物, 并发症

Abstract:

DBJECTIVE: To evaluate the efficacy of traditional Chinese medicine in the treatment of complications following cerebrovascular stent placement.
METHODS: A computer screen was performed for Science Direct database and Ei database between January 1960 and October 2009, using key words of “traditional Chinese medicine, stent placement, complication”, and the language was limited to English. At the same time, Chinese Journal Full-text database and Chinese Biomedical Literature database between January 1994 and October 2009 were searched for related articles, using key words of “ traditional Chinese medicine, cerebral blood vessels, stent placement, complications’’, and the language was limited to Chinese. In addition, several monographs were manually consulted. The basic and clinical trials addressing the prevention and treatment of traditional Chinese medicine on the complications following cerebrovascular stenting were included.
RESULTS: Subsequent to the cerebrovascular stent placement, the traditional Chinese medicine interventions include benefiting Qi, invigorating blood circulation, and eliminating phlegm, which all serve as the basic approach, in addition these interventions are accompanied by relieving Qi and stagnancy in liver, soothing the nerves and benefiting water, cooling blood and stopping bleeding. The commonly used traditional Chinese medicine compound is consisted of Shengmai San, Buyang Huanwu decoction, Xuefu Zhuyu decoction, sini decoction and resist decoction. Modern pharmacological studies have shown that a large number of traditional Chinese medicine and compound which are always used to benefit Qi, invigorate blood circulation, dissipate blood stasis and eliminate phlegm, can effectively prevent the complications following cerebrovascular stent placement through a multi-component, multi-target, multi-channel integration regulatory role.
CONCLUSION: The traditional Chinese medicine interventions during the peri-operative period of cerebral vascular stent placement exhibit a feature of Chinese medicine and play an important role for improving the success rate of surgery, preventing and reducting peri-operative period and long-term complications.

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