Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (47): 7689-7696.doi: 10.3969/j.issn.2095-4344.2014.47.026

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Platelet-rich plasma for treatment of ischiogluteal bursitis

Shen Zi-wei, Lin Zi-hong, Zheng Qiu-jian, Wang Liang-ze, Ye Sheng-long, Li Sheng, Qian Si-nong   

  1. Guangdong Academy of Medical Sciences Guangdong General Hospital), Guangzhou 510080, Guangdong Province, China
  • Revised:2014-10-23 Online:2014-11-19 Published:2014-11-19
  • About author:Shen Zi-wei, Studying for master’s degree, Guangdong Academy of Medical Sciences (Guangdong General Hospital), Guangzhou 510080, Guangdong Province, China

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Abstract:

BACKGROUND: Ischiogluteal bursitis has been recognized for a long time, but its treatment still limits to local blocking injection and surgery methods that were developed 40 years ago.
OBJECTIVE: To observe the efficacy of platelet-rich plasma on ischiogluteal bursitis.
METHODS: Data of 15 patients with ischiogluteal bursitis were collected. All the patients with ischiogluteal bursitis were treated with bilateral platelet-rich plasma (n=10) or local blocking injection (n=5). Patients’ outcomes were assessed by visual analogue scale, the Treatment Satisfaction Questionnaire for Medication (TSQM) Version II and recurrence rate. The follow-up time was from 6 to 14 months.
RESULTS AND CONCLUSION: There was no statistical difference in visual analogue scale score between the platelet-rich plasma group and local blocking group (F=0.219, P=0.643), but the score of visual analogue scale in the platelet-rich plasma group was higher during short-term follow-up (within 1 week after treatment), but lower in the long-term follow-up. In the aspects of overall satisfaction score, clinical effectiveness and side effects, the platelet-rich plasma group was inferior to the local blocking group at short-term follow-up, especially at 1 week after treatment; however, these scores became better in the platelet-rich plasma group than the local blocking group during the long-term follow-up period. In addition, no statistical difference in the convenience score was found between the two groups. At the last follow-up, the recurrence rate in the platelet-rich plasma group was lower than that in the local blocking group. Both the platelet-rich plasma and local blocking injection can significantly reduce the pain of patients with ischiogluteal bursitis. Local blocking injection has better short-term effectiveness. Platelet-rich plasma injection works moderately, but its effectiveness can last for longer time, and the recurrence rate is lower.


中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程


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Key words: platelet-rich plasma, bursitis, ischium

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