Chinese Journal of Tissue Engineering Research ›› 2023, Vol. 27 ›› Issue (20): 3236-3241.doi: 10.12307/2023.433
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Liu Yunqin1, Lin Li2, Xiao Wenhao1, Ji Qiuming1, Liu Yanqin3
Received:
2022-04-24
Accepted:
2022-06-15
Online:
2023-07-18
Published:
2022-11-19
Contact:
Liu Yunqin, Associate chief physician, Department of Psychiatry, Wuhan Wudong Hospital, Wuhan 430084, Hubei Province, China
About author:
Liu Yanqin, Associate chief nurse, Operating Room, Wuhan Wudong Hospital, Wuhan 430084, Hubei Province, China
Supported by:
CLC Number:
Liu Yunqin, Lin Li, Xiao Wenhao, Ji Qiuming, Liu Yanqin. Effects of icariin on NRG1-ErbB signaling pathways in hippocampus of schizophrenia rats[J]. Chinese Journal of Tissue Engineering Research, 2023, 27(20): 3236-3241.
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2.1 实验动物数量分析 48只大鼠全部进入结果分析。 2.2 各组大鼠行为学表现 逃避潜伏期采用重复测量资料方差分析,组间和时间效应显著(F=97.991,378.088,P < 0.001),进一步采用多重分析。与正常组比较,模型组大鼠刻板行为评分、自发活动总路程和逃避潜伏期明显增加(P < 0.05),穿台次数明显减少(P < 0.05)。与模型组比较,淫羊藿苷低剂量组大鼠刻板行为评分和逃避潜伏期明显减少(P < 0.05),穿台次数明显增加(P < 0.05);淫羊藿苷高剂量组刻板行为评分、自发活动总路程和逃避潜伏期明显减少(P < 0.05),穿台次数明显增加(P < 0.05)。淫羊藿苷高剂量组大鼠刻板行为评分、逃避潜伏期(第3-5天)明显低于淫羊藿苷低剂量组(P < 0.05),见表1,2。"
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