Numerical analysis of knee articular cartilage under compound loads

doi:10.3969/j.issn.2095-4344.0396

Abstract

Abstract:

BACKGROUND: By establishing biphasic cartilage model and simulating solid matrix stress under compressive load, the effect of mechanical stimulation on arthritis is investigated at molecular level. However, the changes of loads and movement angle of cartilage in actual exercise are little reported.

OBJECTIVE: To reveal the mechanical characteristics of knee joint cartilage under compression, rolling, sliding or rotation and combined loads.

METHODS: An articular cartilage model considering the role of the calcified layer and subchondral bone was established, which was closer to the natural physiological structure of cartilage. The motion of the knee joint was the relative motion between tibial plateau and distal femur, which was simplified as a geometric model of rigid sphere acting on the plane cartilage. Considering the kinematics of flexion, extension, introversion, extroversion, internal rotation and external rotation, the three-dimensional finite element model of knee joint during walking under combined load was established. The mechanical characteristics of knee joint cartilage under compression, rolling, sliding or rotation and combined loads were analyzed.

RESULTS AND CONCLUSION: (1) In the gait process, the maximum stress area of articular cartilage was distributed on the subchondral bone. (2) With the progress of the compression, the Mises stress, strain and pore pressure increased with the compressive load increasing, and the increase range showed a trend of nonlinear decrease. (3) These results imply that the rolling load is closest to the total combined loads, which provides reference for the in vitro functional cultivation of tissue-engineered cartilage and protocol design.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Cartilage, Articular, Gait, Numerical Analysis, Computer-Assisted, Tissue Engineering

CLC Number:

R446

Li Jinjun, Men Yutao, Zhang Chunqiu . Numerical analysis of knee articular cartilage under compound loads[J]. Chinese Journal of Tissue Engineering Research, 2019, 23(8): 1208-1213.

Figures/Tables 2

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