Perforation of the pulp chamber floor: repair with mineral trioxide aggregate, light-cured glass ionomer cement and light-cured calcium hydroxide

doi:10.3969/j.issn.2095-4344.0654

Abstract

Abstract:

BACKGROUND: Mineral trioxide aggregate (MTA), a new biomaterial, has significant advantages in sealing, biocompatibility, antibacterial activity, which can be used as the first choice for the repair of perforated pulp chamber floor. However, the clinical efficacy of MTA has not been widely verified.

OBJECTIVE: To compare the therapeutic effects of light-cured glass ionomer cement (LGIC), light-cured calcium hydroxide (LCH) and MTA in the repair of perforation of the pulp chamber floor.

METHODS: One hundred and fifty-three patients with perforation of the pulp chamber floor who were treated at the Department of Dentistry, Binzhou Medical University Hospital from May 2013 to May 2015 were selected as the research objects. According to the simple random sampling method, these patients were randomized into MTA group, LGIC group and LCH group, with 51 cases in each group. The MTA, LGIC and LCH were used to repair the affected teeth in corresponding groups. One-year post-treatment therapeutic effect, the repair time of periodontal hard tissue, the incidence of adverse reactions and the satisfaction of the patients were compared among the three groups. Meanwhile, the clinical efficacy on the affected teeth with different characteristics (including different position, perforation diameter and perforation reason) in the MTA group was compared.

RESULTS AND CONCLUSION: The total effective rate and overall satisfaction rate of MTA group were significantly higher than those in the other two groups (P < 0.05), while the incidence of adverse reactions was significantly lower in the MTA group than the other two groups (P < 0.05). When the perforation diameter was < 2 mm, the percentage of patients who underwent the repair of periodontal hard tissue within 3 months was significantly higher in the MTA group than the LGIC group and LCH group (P < 0.05). Moreover, in the MTA group, the total effective rate with the perforation diameter < 2 mm was significantly higher than with the perforation diameter ≥ 2 mm (P < 0.05), and the total effective rate of the iatrogenic group was significantly higher than that of the carious group (P < 0.05). Logistic regression results showed that the diameter of perforation and the cause of perforation were both significant factors influencing the clinical efficacy of MTA (P < 0.05). These results confirm that MTA has a significant effect on the repair of the perforation of the pulp chamber floor, characterized by relatively short repair time and few adverse reactions. Therefore, MTA can be used as the first choice for the restoration of the affected teeth, and its clinical efficacy is related to the size and the cause of the affected teeth.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Tissue Engineering, Biocompatible Materials, Periodontium

CLC Number:

R318

Wang Jing, Wang Mengyang, Feng Qiaoqiao, Sun Jijun, Ci Haosu. Perforation of the pulp chamber floor: repair with mineral trioxide aggregate, light-cured glass ionomer cement and light-cured calcium hydroxide[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(34): 5458-5463.

Figures/Tables 8

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