Changes of bone mass after concentrated growth factor liquid applied in dental implant surgery with guided bone regeneration

doi:10.3969/j.issn.2095-4344.2017.08.007

Abstract

Abstract:

BACKGROUND: The osteogenesis effects of concentrated growth factors (CGF) gel have been studied, butlittle has been reported on CGF liquid.
OBJECTIVE: To explore the bone mass changes after CGF is used in the dental implant surgery with guided bone regeneration (GBR) in patients with upper anterior tooth labial bone defect, and to evaluate the effect of CGF liquid combined with Bio-Oss bone meal on bone augmentation.
METHODS: Fifty patients with single anterior tooth labial bone defect were enrolled and randomly divided into experimental and control groups (n=25 per group). Patients in both groups underwent dental implant surgery with GBR. CGF liqiud, Bio-Oss bone meal and biological membrane were used in the experimental group, and Bio-Oss bone meal and biological membrane used in the control group.
RESULTS AND CONCLSUION: All patients healed well according to the successful criteria. Six months postoperatively, there was no significant difference in the thickness changes of labial bone between two groups (P > 0.05). From 6 months to 12 months after operation, the thickness changes of labial bone in the experimental group was significantly less than that in the control group (P < 0.05). Our findings indicate that CGF liquid combined with Bio-Oss bone meal makes good effect on dental implantation of patients with anterior tooth labial bone defect. CGF liquid also contributes to reduce the labial bone resorption of the implant after functional loading.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Tooth, Bone Regeneration, Tissue Engineering

CLC Number:

R318

Zhang Lu1, 2, Wang Pin2, Guo Ling2, Liu Min2 . Changes of bone mass after concentrated growth factor liquid applied in dental implant surgery with guided bone regeneration[J]. Chinese Journal of Tissue Engineering Research, 2017, 21(8): 1186-1191.

Figures/Tables 3

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