Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (6): 883-887.doi: 10.3969/j.issn.2095-4344.2017.06.011

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Core decompression combined with beta-tricalcium phosphate bioceramics for early non-traumatic osteonecrosis of the femoral head

He Sheng-mao, Lin Li-jun, Wang Cheng-qiang, Li Qi
  

  1. Orthopedic Center, Zhujiang Hospital of Southern Medical University, Guangzhou 510282, Guangdong Province, China
  • Received:2017-01-20 Online:2017-02-28 Published:2017-03-16
  • Contact: Li Qi, M.D., Doctoral supervisor, Professor, Chief physician, Orthopedic Center, Zhujiang Hospital of Southern Medical University, Guangzhou 510282, Guangdong Province, China
  • About author:He Sheng-mao, Studying for master’s degree, Attending physician, Orthopedic Center, Zhujiang Hospital of Southern Medical University, Guangzhou 510282, Guangdong Province, China
  • Supported by:

    the Guangdong Provincial Science and Technology Program, No. 2014A020212668

Abstract:

BACKGROUND: There are numerous laboratory reports concerning β-tricalcium phosphate (β-TCP)
bioceramics; however, its application in the treatment of osteonecrosis of the femoral head (ONFH) is rarely reported.
OBJECTIVE: To analyze the short-term efficacy of core decompression combined with β-TCP bioceramics in the treatment of ARCO I/II /IIIA non-traumatic ONFH.
METHODS: Twelve patients (16 hips) suffered from ARCO I/II /IIIA non-traumatic ONFH were treated by core decompression combined with β-TCP implantation. The Harris hip scores (HHS) and radiological observation were performed before and after treatment. The HHS at the last follow-up or the HHS prior to the radiographs showing deterioration or severe complication occurrence was recorded.
RESULTS AND CONCLUSION: All patients were followed up for 19 months averagely (11-30 months) and no fracture, infection and other complications occurred. The HHS significantly increased from (73.61±3.70) to (84.88±7.11) points after treatment (P < 0.001). The postoperative outcome was excellent in five cases with five hips, good in five cases with nine hips, mild in one case with one hip, poor in one case with one hip, and the excellent and good rate was 87.5% (14/16). The radiographs of only one case of ARCO IIC and one case of ARCO IIIA showed deterioration, and the latter was given the total hip arthroplasty. These results indicate that the core decompression combined with β-TCP implantation achieve short-term efficacy for ARCO I/II /IIIA non-traumatic ONFH.

Key words: Femur Head Necrosis, Decompression, Surgical, Calcium Phosphates, Tissue Engineering

CLC Number: