Low frequency-pulsed electromagnetic fields promote bone healing: 
a Meta-analysis

doi:10.3969/j.issn.2095-4344.2017.32.025

Abstract

Abstract:

BACKGROUND: Low frequency-pulsed electromagnetic fields (LF-PEMFs) have been confirmed to not only treat delayed bone union or nonunion, but also be effective for fresh bone fractures, ostectomy and fatigue fractures.
OBJECTIVE: To systematically evaluate the efficacy and safety of LF-PEMFs for bone healing.
METHODS: CNKI and PubMed databases were retrieved for the randomized controlled trials concerning LF-PEMFs promoting bone healing published from January 1985 to May 2016. Meta-analysis was conducted on RevMan 5.1 software after data management and quality assessment.
RESULTS AND CONCLUSION: Thirteen eligible literatures were enrolled, involving 1244 patients. Meta-analysis showed that the overall effectiveness and bone mineral density in the LF-PEMFs group were significantly higher than those in the control group. The healing time in the LF-PEMFs group was significantly shorter than that in the control group. These results suggest that LF-PEMFs show high efficacy and safety for bone healing, and also can markedly shorten the healing time. However, more high-quality multi-center, large-scale randomized controlled trials are still needed to testify all above conclusions.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Electromagnetic Fields, Fractures, Bone, Meta-Analysis

CLC Number:

R318

Zhao Xin-juan1, Zhang Jing2, Yin Bo2, Kang Yi-ting2. Low frequency-pulsed electromagnetic fields promote bone healing:
a Meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2017, 21(32): 5234-5239.

Figures/Tables 3

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