Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (32): 5243-5248.doi: 10.3969/j.issn.2095-4344.2712

Previous Articles    

Prospects for 3D printing in the treatment of cerebral aneurysm

Zhang Yaochun1, Zheng Lifang2, Liu Rong3   

  1. 1Clinical College of Wuhan University of Science and Technology, Wuhan 430080, Hubei Province, China; 2Shenzhen Yantian District People's Hospital, Shenzhen 518000, Guangdong Province, China; 3Institute of Medical Innovation and Transformation, Puren Hospital, Wuhan University of Science and Technology, Wuhan 430081, Hubei Province, China

  • Received:2019-07-24 Revised:2019-07-27 Accepted:2020-01-18 Online:2020-11-18 Published:2020-09-26
  • Contact: Liu Rong, MD, Associate chief physician, Master’s supervisor, Institute of Medical Innovation and Transformation, Puren Hospital, Wuhan University of Science and Technology, Wuhan 430081, Hubei Province, China
  • About author:Zhang Yaochun, Master candidate, Clinical College of Wuhan University of Science and Technology, Wuhan 430080, Hubei Province, China Zheng Lifang, Master, Chief physician, Shenzhen Yantian District People's Hospital, Shenzhen 518000, Guangdong Province, China
  • Supported by:
    the Key Project of Metallurgical Safety and Health Branch of China Metal Society, No. 18-02-21; the Hubei Provincial Health and Family Planning Commission Joint Fund Innovation Team Project, No. WJ2018H0042

PDF

140

Abstract:

BACKGROUND: Interventional treatment can also be used as a palliative treatment for patients who cannot be surgically removed. However, the positioning of the lesion at the beginning of the operation or the catheter during the interventional treatment can only be accurately and clearly displayed through the two-dimensional image, and is related to the operator’s own experience and understanding of the image. The 3D printing model is a physical model with high simulation and individualized features, and has the advantages of individualization and precision in the medical field. It is currently widely used in orthopedics, oral and maxillofacial surgery, but the application in the treatment of craniocerebral aneurysms is rarely reported.

OBJECTIVE: To summarize the classification and treatment status of cerebral aneurysms, and to prospect the application prospect of 3D printing technology in the treatment of cerebral aneurysms.

METHODS: The authors retrieved CNKI, WanFang, PubMed, and EI database. The search terms were “cerebral aneurysm, clinical classification, treatment, 3D printing”. A total of 96 relevant literatures were retrieved, and 51 articles were summarized according to the inclusion and exclusion criteria. Specifically, it included the classification of cerebral aneurysms, craniotomy and interventional therapy, and the application status of 3D printing technology.

RESULTS AND CONCLUSION: At present, the treatment methods of cerebral aneurysms commonly used in clinical practice have their own advantages and limitations. In this case, 3D visualization and 3D printing technology are proposed, which is an important supplement for the clinical treatment of patients with cerebral aneurysms. It can display organ anatomy and spatial structure more intuitively and accurately through operations such as enlargement, rotation and transparency. At the same time, it can accurately locate the aneurysm site, calculate the aneurysm size and volume, and define the aneurysm morphology. This is significant in preoperative diagnosis, planning of surgery, precise operation during surgery, and improvement of surgical success rate for the brain aneurysm. Simultaneously, the solid model of 3D printing is also widely used in the aspects of disease communication and training of resident surgical operations. By summarizing the research progress of 3D printing technology in the treatment of cerebral aneurysms, we have a clearer understanding of the application of 3D visualization and 3D printing technology. Whether it is combined with fluid mechanics for hemodynamic research or refined treatment based on existing treatment schemes, it has promoted the development of clinical research.

Key words: cerebral aneurysm, clinical typing, treatment, 3D printing, 3D visualization

CLC Number: