Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (12): 1911-1916.doi: 10.3969/j.issn.2095-4344.2528

Previous Articles     Next Articles

Effect of different defect areas of medial femoral condyle cartilage on peripheral cartilage stress: three-dimensional finite element analysis

Zhang Yeming1, 2, Wu Di1, Zhang Ling3, Liu Min2, Yu Yong1, Cui Jiewen1, Yuan Bingqian1, Li Qing1   

  1. 1Department of Orthopedics, First Affiliated Hospital of Kunming Medical University, Yunnan Institute of Orthopedics, Kunming 650000, Yunnan Province, China; 2People’s Hospital of Xiangyun, Dali 672100, Yunnan Province, China; 3Zhaotong Hospital of Traditional Chinese Medicine, Zhaotong 657000, Yunnan Province, China
  • Received:2019-07-25 Revised:2019-08-01 Accepted:2019-09-07 Online:2020-04-28 Published:2020-03-02
  • Contact: Li Qing, MD, Associate chief physician, Associate professor, Department of Orthopedics, First Affiliated Hospital of Kunming Medical University, Yunnan Institute of Orthopedics, Kunming 650000, Yunnan Province, China
  • About author:Zhang Yeming, Master candidate, Physician, Department of Orthopedics, First Affiliated Hospital of Kunming Medical University, Yunnan Institute of Orthopedics, Kunming 650000, Yunnan Province, China; People’s Hospital of Xiangyun, Dali 672100, Yunnan Province, China

PDF

53

Abstract:

BACKGROUND: Although it has been found in many studies that three-dimensional finite element analysis can be used in the study of knee joint biomechanics, there are few researches on different defect areas of medial condyle cartilage of the femur. 

OBJECTIVE: To analyze the stress change trend of perimeter articular cartilage before and after the occurrence of different defect areas of medial femoral condyle cartilage, providing biomechanical data for patients with knee medial femoral condyle cartilage defect.

METHODS: One normal adult had been selected to establish a three-dimensional finite element model. Material mechanical properties were input to Abaques software with divided grid model. After controlling boundary condition with mechanical load, structural nonlinear finite element was calculated. First, the load stress distribution of knee cartilage and meniscus was observed under normal stress. Articular cartilage stress distribution was observed with load conditions in different defects (0, 6, 8, 10, 12, 14, 16, 18 and 20 mm) of medial femoral condyle. The stress changes on the cartilage were analyzed during the defect of medial femoral condyle. This study was approved by the Ethics Committee of First Affiliated Hospital of Kunming Medical University. The volunteer signed the informed consent.

RESULTS AND CONCLUSION: (1) Material properties, boundary conditions and the introduction of loads were defined successfully. The stress cloud chart and its stress data were obtained from different diameter defects of cartilage in medial condyle of knee joint. According to statistical analysis, the stress on the femoral condyle and tibial plateau cartilage had significant changes compared with no defects when the medial femoral condyle cartilage had defects of 10 mm (area 0.78 cm2) and 12 mm (area 1.13 cm2). (2) The stress change trend of the cartilage of the medial condyle of the knee joint under the condition of different diameter defects was calculated based on the analysis of the application of three-dimensional finite element method. (3) Results suggest that the defect with the diameter of 10 mm (area 0.78 cm2) of medial femoral condyle may be the minimum diameter advised for operation intervention of cartilage repair.   

Key words: medial condylar cartilage of femur, different defect area, peripheral cartilage, stress, three-dimensional finite element analysis

CLC Number: