Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (22): 3458-3463.doi: 10.3969/j.issn.2095-4344.2017.22.003

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Impaction bone grafting with morselized bone and bone paste for acetabular defects in adult Crowe III type developmental dysplasia of the hip

Wu Tian-hao, Guo Jiang, Zhang Cai-dong, Fan Zhong-wei, Wang Sen, Liu Shao-feng, Tan Mei-yun
  

  1. Department of Bone and Joint Surgery, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
  • Received:2017-03-15 Online:2017-08-08 Published:2017-09-01
  • Contact: Tan Mei-yun, Department of Bone and Joint Surgery, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
  • About author:Wu Tian-hao, Studying for master’s degree, Department of Bone and Joint Surgery, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
  • Supported by:

    the Funding Project of Sichuan Provincial Education Department, No. 12ZB062

Abstract:

BACKGROUND: Considering the risk of lack of bone in revision and the bone coverage of component, it is advisable to use bone grafting to increase bone stock in patients with adult Crowe type III developmental dysplasia of the hip (DDH) in the first total hip arthroplasty (THA).
OBJECTIVE: To investigate the effectiveness of impaction bone grafting with morselized bone and bone paste for acetabular defects of adult Crowe type III DDH in THA.    
METHODS: Forty cases (45 hips) of Crowe type III DDH were enrolled, including 8 males and 32 females, aged 31-68 years. All the components were reconstructed at the anatomic acetabulum combined with deepening acetabulum and putting the centre of rotation medially and distally during THA procedures. The patients were all followed up and evaluated with Harris score, limp length, displacement of the centre of rotation, cup coverage, and postoperative complications.
RESULTS AND CONCLUSION: The average follow-up was 32.7 months. Acetabular rotation centers of all the cases were recovered (near) to normal. The incisions healed by first intention and there was no complication such as infection, dislocation, prosthesis loosening. The acetabular cup prosthesis did not displace and was covered well by bone at the last follow-up, the grafted bone particles got radiological osseointegration and the bone sclerosis zone disappeared. No radiolucent lines and screw fracture were detected. The Harris scores of affected hips at the last follow-up were significantly higher than those before surgery(P=0). The average leg length was increased (2.31±0.18) cm. The mean cup coverage was 78.1%. The postoperative horizontal and vertical distance of the hip center were shorter than those before surgery (P=0). Reconstructing the acetabulum with autogenous morselized bone graft impaction can effectively restore the acetabular coverage, maintain the stability of acetabular cup and provide better relative bone stock in THA for Crowe type III DDH in adult, and moreover, the short-term effect is satisfactory.  

Key words: Arthroplasty, Replacement, Hip, Transplantation, Autologous, Tissue Engineering

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