Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (17): 2474-2480.doi: 10.3969/j.issn.2095-4344.2016.17.006

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Risk of deep venous thrombosis among patients undergoing knee arthroscopy based on Caprini risk assessment

Xu Liu-hai, Zeng Yong, Huang Wei, Wang Mao-peng, Que Xiang-yong, Yi Chun-yan   

  1. Department of Orthopedics, Renhe Hospital of Three Gorges University, Yichang 443001, Hubei Province, China
  • Received:2016-02-26 Online:2016-04-22 Published:2016-04-22
  • Contact: Zeng Yong, Associate chief physician, Department of Orthopedics, Renhe Hospital of Three Gorges University, Yichang 443001, Hubei Province, China
  • About author:Xu Liu-hai, Attending physician, Department of Orthopedics, Renhe Hospital of Three Gorges University, Yichang 443001, Hubei Province, China
  • Supported by:

    the Sciencific Research Project of Health and Family Planning Commission of Hubei Province, No. WJ2015084

Abstract:

BACKGROUND: After arthroscopic knee surgery, deep vein thrombosis easily occurs. Currently, there were no specific clinical manifestations in deep vein thrombosis, so a fast, convenient and reliable risk assessment tool was needed to evaluate the clinical high-risk groups for prevention and intervention. The effectiveness of Caprini Risk Assessment Scale used in thrombosis risk assessment has been confirmed by a large number of researches, but the current domestic research is less. 

OBJECTIVE: To verify the validity of Caprini risk assessment scale in evaluations of high deep venous thrombosis risk patients among knee arthroscopy patients, and to explore effective strategies for prevention of deep vein thrombosis in patients undergoing knee arthroscopic surgery.
METHODS: A case-control study design was used to collect 49 deep vein thrombosis patients admitted to the Department of Orthopedics, Renhe Hospital of Three Gorges University from January 2008 to June 2015 as case group, and randomly selected 98 patients admitted during the same period of non-deep vein thrombosis patients as control group. Caprini risk assessment scale was used to assess risk assessment and risk grading of deep venous thrombosis, and to explore the correlation between risk classification and risk of deep vein thrombosis.
RESULTS AND CONCLUSION: (1) Basic conditions comparison: application time of tourniquet, the proportion of smoking patients, and proportion of deep venous thrombosis and (or) the history of pulmonary thromboembolism were higher in the case group than in the control group (P < 0.05). (2) Caprini score was significantly higher in the case group than in the control group (P < 0.001). In the case group, the proportion of very high risk patients (53%) was highest, followed by high risk (25%), totally 78%. In the control group, the proportion of high risk patients (32%) was highest, followed by low risk (29%). Significant differences in above risk degree analysis were identified between the two groups (P < 0.001). (3) Deep venous thrombosis and (or) the history of pulmonary thromboembolism was positively correlated with Caprini score in the case and control groups (P < 0.05). Caprini score was positively associated with application time of tourniquet in the case group (P < 0.05). (4) Logistic regression analysis of Caprini risk classification and the risk of deep vein thrombosis: with increased caprini risk classification, the risk of deep vein thrombosis increased significantly. The risk of deep venous thrombosis in patients with high risk and very high risk was 2.130 and 11.786 times of patients with low risk, respectively. (5) These results indicate that Caprini risk assessment model can effectively assess the risk of deep vein thrombosis among patients receiving knee arthroscopy.
中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

Key words: Arthroscopes, Venous Thrombosis, Pulmonary Embolism, Tissue Engineering