BACKGROUND: It is very important to early diagnosis of lower extremity deep vein thrombosis after total hip replacement, which also has very important meaning for the timely treatment and judging the curative effect.
OBJECTIVE: To study the blood changes of the patients complicated with lower extremity deep vein thrombosis after hip joint replacement, so as to provide the reference for the early prediction and intervention.
METHODS: Among 60 cases of hip joint replacement patients who received the treatment from January 2009 to  September 2014, there were 32 cases of postoperative patients complicated with lower extremity deep vein thrombosis (lower extremity deep vein thrombosis group), 28 cases without concurrent lower extremity deep vein thrombosis (non-lower extremity deep vein thrombosis group). The change of the blood rheology index of patients was detected at the 1st, 3rd, 5th days after hip joint replacement.
RESULTS AND CONCLUSION: The detection results showed that the various coagulation markers in the lower extremity deep vein thrombosis group after the replacement were abnormally higher than those in the non-lower extremity deep vein thrombosis group, which showed that the hypercoagulability attitudes of patients after hip joint replacement closely related to the occurrence of lower extremity deep vein thrombosis, however, the D- dimer and fibrinogen levels of patients at the 3rd and 5th days after hip joint replacement in lower extremity deep vein thrombosis group were significantly higher than non-lower extremity deep vein thrombosis group, which showed that the increase of D- dimer and fibrinogen levels was positively correlated with the occurrence of lower extremity deep vein thrombosis after hip joint replacement. These results suggest that patients should undergo dynamic blood monitoring after hip joint replacement. If the test results were continuously increased, we should doubt whether the occurrence of thrombosis, and then take preventive measures as early as possible.