Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (43): 7047-7052.doi: 10.3969/j.issn.2095-4344.2015.43.029

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Clinical application of a new skin-stretching device

Dang Zheng-jie, Zhang Bao-quan, Wang Shou-feng, Yang Xin-gang, Gao Wei   

  1. Department of Burn and Plastic Surgery, Laigang Group Co. Hospital, Laiwu 271126, Shandong Province, China
  • Received:2015-07-27 Online:2015-10-15 Published:2015-10-15
  • About author:Dang Zheng-jie, Master, Associate chief physician, Department of Burn and Plastic Surgery, Laigang Group Co. Hospital, Laiwu 271126, Shandong Province, China

Abstract:

BACKGROUND: Previously deep burn wound or skin defects are generally repaired with skin grafting or flap of skin grafting. Obvious scar hyperplasia usually appears after operation, which requires multiple surgeries. Meanwhile, patients have to suffer from great pain and bear high cost.

OBJECTIVE: To observe the clinical effects on deep wounds by continuous traction of self-designed skin-stretching device (patent No. ZL 2012 2 0022443.7).
METHODS: Thirty patients with deep burn wound, skin defect or funicular scar were enrolled, including 22 males and 8 females, aged 18-49 years, and randomly divided into two groups. Skin-stretching device was adopted for skin traction treatment. Twenty cases underwent skin traction from 1 kg pulling force to 5 kg, with an increase of  1 kg per 2 days, 6 hours a day for 10 days. Blood flow at the beginning, 1, 5, 10, 15, 20, 30, 60 minutes of the skin traction, and the changes of wound edge skin as well as histological changes of the skin were observed. Of the remaining 10 cases, 2, 6, and 2 cases underwent skin traction of 2, 4, 7 kg, respectively. Blood flow and skin changes were also observed to find out the most suitable and safe force.
RESULTS AND CONLUSION: All the 30 cases achieved primary healing without necrosis of skin, infection or peripheral circulatory disorders, and the appearance and function recovered well. The healing time was 8-24 days. The skin-stretching device was most safe under 4 kg pulling force, by which, there was neither blood circulation obstacle nor tear of skin. After traction, the skin blood flow and the number of cells increased, especially the epithelial basal cells. The collagen fibers became thicker and denser, and the elastic fibers regenerated significantly; the fibroblasts and capillary density increased. It has been proved that we can better close the wound and reduce scar formation effectively with the self-designed skin-stretching device for skin traction. 
中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Skin, Traction, Tissue Engineering