Percutaneous verterbroplasty with bone cement injection for osteoporotic vertebral compression fractures via transpedicular approach

doi:10.3969/j.issn.2095-4344.2015.30.026

Abstract

Abstract:

BACKGROUND: Studies have shown that percutaneous vertebroplasty is a better method to repair osteoporotic vertebral compression fractures, but there are still less specific schemes of transpedicular approach. Whether unipedicular or bipedicular approach is preferred is still controversial.

OBJECTIVE: To compare the clinical efficacy of percutaneous verterbroplasty via unipedicular and bipedicular approach on osteoporotic vertebral compression fractures.

METHODS: Totally 118 patients with osteoporotic vertebral compression fractures who had been admitted at the Department of Orthopedics, the First People’s Hospital of Kashi from June 2010 to June 2013 and followed up over 1 year were enrolled and randomly divided into unipedicular and bipedicular groups, with 59 in each group.
These two groups were compared in terms of bone cement volume, bone cement leakage, kyphosis correction, vertebral height restoration, visual analog scale score, Oswestry disability index, activity of daily living scale score, SF-36 score, and postoperative complications.

RESULTS AND CONCLUSION: The cement leakage rate was lower in the unipedicular group (34%) than the bipedicular group (37.3%), but there was no significant difference (P=0.701 > 0.05). The kyphosis correction and scoliosis correction had no statistical significance between the two groups (P > 0.05). The mean vertebral height was improved significantly in both two groups at 1 year after operation (P < 0.05), but there was no difference between the two groups before and after operation (P > 0.05). There were also no significant differences between the two groups in terms of visual analog scale score, Oswestry disability index, activity of daily living scale score, SF-36 score before and after operation, but these indexes were all improved significantly in each group at 1 year after operation than before operation (P < 0.05). The bone cement amount of the unipedicular group was lower than that of the bipedicular group (P=0.001 < 0.05), and the operation time was also shorter in the unipedicular group than the bipedicular group (P=0.000 < 0.05). No serious complications occurred in the two groups. These findings indicate that percutaneous verterbroplasty via unipedicular and bipedicular approach has good analgesic and repair outcomes in patients with osteoporotic vertebral compression fractures, and the unipedicular approach is better than the bipedicular approach in the following aspects: less bone cement volume, lower cement leakage and shorter operation time.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Thoracic Vertebrae, Lumbar Vertebrae, Fractures, Bone, Vertebroplasty

CLC Number:

R318

Cai Jia, Hao Ying-wei, Li Chao, Yang Hua-qun. Percutaneous verterbroplasty with bone cement injection for osteoporotic vertebral compression fractures via transpedicular approach[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(30): 4892-4897.

Figures/Tables 3

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