Materials biocompatibility in the internal fixation of pelvic fracture combined with acetabular fracture

doi:10.3969/j.issn.2095-4344.2015.25.031

Abstract

Abstract:

BACKGROUND: Pelvic fractures combined with acetabular fractures are mostly caused by high-energy violence, often accompanied by severe complications and high mortality, and surgical fixation is preferred in most cases.
OBJECTIVE: To investigate the internal fixation of pelvic fracture combined with acetabular fracture and to analyze the material biocompatibility.
METHODS: A computer-based search of Wanfang, CNKI and PubMed databases was performed for articles related to the internal fixation of pelvic fracture combined with acetabular fracture and material biocompatibility published from 2005 to 2014. The keywords were “pelvis fractures, acetabulum fractures, internal fixators, materials” in Chinese and English, respectively. Articles published in authoritative journals or recently were preferred, and finally 29 articles were enrolled in result analysis.
RESULTS AND CONCLUSION: Steel plate reconstruction or screw internal fixation is often used for clinical treatment of pelvic fracture combined with acetabular fracture. Titanium plate is often chosen with similar elastic modulus to the bone and good biocompatibility. The titanium plate is pre-bended before implantation to match the bone surface of the fracture site. Absorbable screws have good histocompatibility and non-toxic side effects, which can avoid the electrolysis and corrosion of metal screws and maintain certain strength in early period of internal fixation; over time, the fracture is gradually healed, the material strength gradually decreases, and the material is finally degraded into water and carbon dioxide to achieve good clinical outcomes. It is difficult and high-risk for treatment of pelvic fracture combined with acetabular fractures, and active treatment and damage control are recommended as soon as possible. A reasonable treatment plan can be developed based on the type of fracture. Plate internal fixation and minimally invasive fixation developed by the three-dimensional reconstruction techniques show a great progress in fracture treatment, which have broad clinical application prospects.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Biocompatible Materials, Bone Remodeling, Bone Nails, Pelvis, Acetabulum

CLC Number:

R318

Gao Ming-jie, Tao Jie, Zhou Zi-hui, Du Lin. Materials biocompatibility in the internal fixation of pelvic fracture combined with acetabular fracture[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(25): 4096-4100.

Figures/Tables 2

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