Mesial movement of the rat molars using Ni-Ticoil spring: a model of orthodontic tooth movement

doi:10.3969/j.issn.2095-4344.2014.27.013

Abstract

Abstract:

BACKGROUND: The establishment of model is very crucial in the orthodontic tooth movement experiment. The selection of force and controlling of anchorage may greatly affect experimental results.
OBJECTIVE: To establish an animal model for orthodontic tooth movement.
METHODS: Twenty Wistar rats were included in this study. The root of incisor teeth at upper jaw was drilled and then threaded with a ligature wire (0.3 mm diameter), therefore the alveolar bone and two incisor teeth were ligated. The first molar at right upper jaw was also ligated using a ligature wire (0.2 mm diameter). The experimental teeth were randomly divided into four groups. A Sentalloy closed-coil spring (10 g, 25 g, 50 g) was placed between the maxillary incisors and the maxillary first molar, respectively. Taking the incisor as the anchorage, the molars were given a mesial movement, and control group received no force. On day 14, the dental pulp, dentin and enamel were observed by hematoxylin-eosin staining. The relative depth of dentin resorption was analyzed with Image-Pro Plus software.
RESULTS AND CONCLUSION: A light force (10 g Ni-Ti coil spring) produced irregular enamel resorption and narrowed periodontal membrane space, whereas heavy force (25 g Ni-Ti coil spring) produced irregular dentin and enamel resorption, even heavier force (50 g Ni-Ti coil spring) produced apparent resorption at dental root, which affected the dentin. No statistical difference of the relative depth of dentin resorption was found between the 10 g group and the control group (P > 0.05). The data between other groups showed statistically significant differences (P < 0.05). The mechanical union of the incisors and the mandibular bone efficiently prevents the continuous eruption of the upper incisors, which maintains the anchorage stability. Using Ni-Ti coil spring, a stable, scientific and reliable model of orthodontic tooth movement can be established through mesial movement of the first molars. The optimal force of 10 g is used to move the rat first molar mesially.

中国组织工程研究杂志出版内容重点：肾移植；肝移植；移植；心脏移植；组织移植；皮肤移植；皮瓣移植；血管移植；器官移植；组织工程

全文链接：

Key words: biocompatible materials, orthodontic anchorage, molar, models, animal

CLC Number:

R318

Duan Jiao-hong, Zhang Yang. Mesial movement of the rat molars using Ni-Ticoil spring: a model of orthodontic tooth movement[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(27): 4339-4344.

Figures/Tables 3

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